Argentina captain Juan Martin Fernandez Lobbe has been ruled out of the Dove Men Series clash with Wales on November 16.
The 31-year-old flanker fractured his elbow during Toulon's Top14 defeat to Toulouse on Saturday and is set to be sidelined for up to three months.
"Against Toulouse on Saturday flanker Juan Martin Fernandez Lobbe suffered a fracture of the right elbow," read a Toulon statement.
"He will consult a Marseille professor for surgery. It is estimated he will be unavailable for two to three months."
Argentina also face England, Italy and Ireland during their European tour.
Meanwhile former Wales head coach Sir Graham Henry has left his role as technical advisor to Los Pumas.
The World Cup winning-coach has stepped down to focus on a similar role with Super Rugby side the Blues.
He is just the latest departure from the Pumas' coaching staff after Santiago Phelan quit his role in charge. Phelan had been at the helm for six years but will be replaced by Argentina B coach Daniel Hourcade.
With Liam Williams forced out of the World Cup through injury, lock Luke Charteris and Skills Coach Neil Jenkins say they have to put yesterday's defeat behind them as Wales now look ahead to another physical encounter against South Africa in the quarter-finals of the Rugby World Cup.
Winger Alex Cuthbert is hoping get plenty of ball on the front foot against Australia tomorrow at Twickenham as Wales seek to halt the Wallabies' 10-match winnning streak which stretches back almost seven years.
Wales speedsters Laurie Harries and Jasmine Joyce have just begun a three-month training programme in Guildford with players from Scotland and England as Team GB's Rugby Women Sevens preparations for Rio begin in earnest.
Twelve young people have been selected to follow a one year WRU Coach Core apprenticeship programme. Coach Core was set up by the Royal Foundation of the Duke and Duchess of Cambridge and Prince Harry as part of the Olympics legacy in 2012 and the Duke of Cambridge was on hand to meet the apprentices on their first day in the job. The programme has been funded by the Hunter Foundation.
We look back on the victory over Fiji that makes it three from three for Wales in this World Cup, in a special extra Principality Welsh Rugby Union Podcast. We hear from Wales coach Warren Gatland, captain Sam Warburton, plus Gethin Jenkins, Tomas Francis, Alun Wyn Jones, Dan Biggar, Matthew Morgan and Tyler Morgan, as well as defence coach Shaun Edwards and getting the Fijian perspective from coach John McKee.
Birthday boy Hallam Amos gets the perfect present with his selection on the wing for Wales ahead of Alex Cuthbert as Warren Gatland's men prepare to face England at Twickenham tomorrow in a crucial pool game of the World Cup
Laurie Harries and Jasmine Joyce's playing careers may be at different junctures, but both are a step nearer of reaching their ultimate goal - representing Team GB at next year's Olympic Games at Rio de Janeiro.
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