Newport and Wales centre Andy Marinos is fighting to recover from deep vein thrombosis.
The 30-year-old has the life threatening condition and only early detection has stopped it from claiming his leg.
And now Marinos faces a race against time to recover for the World Cup in Australia this October.
"I'm hoping to be play at least a month and a half of the season and try and stake a claim to get into the World Cup squad, but time is not on my side," admitted Marinos.
Marinos had already been ruled out of this year's Six Nations campaign after suffering damaged ligaments in his foot earlier in the season.
And despite his confidence that he will eventually return to full fitness Marinos has admitted that his leg could never fully recover from the condition also known as, "economy class syndrome," due to its association with long-distance travel.
He said: "Once you've damaged an artery in the leg it's never going to be the same again.
"I had anticipated being back in the middle of March but this is obviously a massive set back."
Marinos first made his Wales debut against Ireland in last season's Six Nations championship and was the highlight of an otherwise disappointing campaign for the Principality.
But even if he does recover from DVT his hopes to travel to Australia could be skuppered due to the connections between the condition and air travel.
And a 60 hour round-trip to Australia for the World Cup is unlikely to be beneficial for Marinos' leg.
However, the South African born star is still positive that he will be able to travel
"I've got to be sensible and manage it correctly on any long haul flights, said Marinos. "I've been advised to take some form of blood thinner to help me out."
As the countdown continues for RWC2015, Tournament Chief Executive Debbie Jevans visited the Millennium Stadium to discuss preparations for the eight matches and reveal the positive news that 100,000 tickets for games at the home of Welsh rugby have sold in the last seven days.
Jason Harries is targeting a first win on the World Series circuit this season with Wales. The series returns to action this weekend in Dubai where Harries is part of a team hoping to build from its efforts in round one in October.
Wales skipper Jevon Groves says his side have addressed a few points from Gold Coast and aim to 'hit the ground running' in the next two rounds of the World Series, kicking off with this weekend in Dubai before heading off to South Africa next week.
Wales Sevens manager Steff Thomas is hopeful his side can build from a quarter-final spot in the opening round of the World Series in Australia when his side take part in the forthcoming double header in Dubai and South Africa.