Saracens scrum-half Kyran Bracken has recovered from the concussion he sustained against Gloucester in the Zurich Premiership three weeks ago and will replace Gloucester's Andy Gomarsall.
Leicester legend Graham Rowntree replaces England lionheart Jason Leonard in the front row, while at the back of the scrum, Wasps No.8 Lawrence Dallaglio replaces Leicester's Lewis Moody.
Both changes are enforced due to injuries.
England: J Robinson (Sale Sharks), D Luger (Harlequins), W Greenwood (Harlequins), C Hodgson (Sale Sharks), B Cohen (Northampton), J Wilkinson (Newcastle), K Bracken (Saracens), G Rowntree (Leicester), S Thompson (Northampton), J White (Bristol Shoguns), M Johnson (Leicester, capt), B Kay (Leicester),R Hill (Saracens), N Back (Leicester), L Dallaglio (Wasps).
Replacements: M Regan (Leeds), M Worsley (London Irish), D Grewcock (Bath), J Worsley (Wasps), A Gomarsall (Gloucester), P Christophers (Bristol Shoguns), J Simpson-Daniel (Gloucester).
MEET THE ENGLISH - Ben Cohen