Holders Llanelli open their defence of the Konica Minolta Cup by breaking new ground when they travel to Brecon in the fourth round on Saturday, December 27.
Llanelli have won Welsh rugby's annual challenge cup 12 times, but have never met Brecon in the 33 seasons of the competition, despite the pair
first playing each other in January 1889.
Cardiff also have new opponents as they travel to Division One club Brynmawr. The Gwent club recently signed fly-half Jason Williams, the
highest-ever league scorer in Wales who has already scored 175 of his club's 290 points this season.
Of the 16 Premier sides entering the last 64, Cross Keys and Carmarthen Quins are paired at Pandy Park and Llandovery will entertain Neath at Church Bank.
The Cup also sees a return for former Wales League and Union scrum-half David Bishop to one of his old clubs. Bishop coaches and occasionally plays for the Old Illtydians on a Cardiff park, and they are drawn away to Ebbw Vale, where the Illtydians scored a memorable 14-11 Cup win in 1994-95.
Wales Head Coach Rob Howley talks to WRU TV's Sebastian Barrett about the 36-man squad he has just named for the forthcoming Under Armour series, which includes two uncapped players, Ospreys duo Sam Davies and Rory Thornton.
Head coach Rowland Phillips is deligthed he can now call BT Sport Cardiff Arms Park home for his Wales Women's side, who launch their international season next month with games against Scotland and UK Armed Forces in the heart of the capital city.
Wales Sevens star Sam Cross has put his home town club of Brynmawr on the map after winning a silver medal at the Rio Olympics with Team GB. His club have now honoured him by naming their players bar after him, as WRU TV discovered at the official launch, recently.
One of the newest members of the Principality Premiership, Bargoed admit it's proving to be a steep learning curve at the highest level, but are determined to become a force to be reckoned with. WRU TV visited the club last weekend when they took on Llanelli.
Table-topping Aberavon travel to north Wales to tackle RGC 1404 as both teams defend unbeaten starts to the season in the Principality Premiership. WRU TV's Graeme Gillespie visited the Wizards to see how their preparations were going for the game of the weekend.
The Half a Game initiative is currently sweeping across Wales and proving a major success. The scheme aims to give every young player at least half a game every weekend. WRU TV recently visited a festival in Narberth where clubs have fully embraced the initiative.
Both Bargoed and Swansea were seeking their first win of the Principality Premiership season this afternoon. It proved a fruitful day for the hosts - not only did they win, but Bargoed claimed a try bonus point.
Cardiff managed to keep their unbeaten record at home intact, but only just as Bridgend made them work extremely hard before the Blue and Blacks secured a hard fought Principality Premiership win at the BT Sport Arms Park last night.
Former Wales back row Andy Powell gives a guided tour of The Wern, home of Merthyr RFC, who are determined to prove a lot of people wrong and make their mark in their first season in the Principality Premiership.