Ponytpool outside-half Byron Hayward joins the Gwent side on loan, and will link up with Mark Meenan at full-back, and Nick Wakeley, Rhys Shorney, Paul Matthews and Andrew Bevan as the threequarters.
Pontypridd select Gareth Wyatt at full-back, while Ceri Sweeney and Gareth Baber return at half-back.
In the forwards Dale McIntosh is picked in the second-row with Robert Sidoli, while in the back-row Academy Under-21 No 8 Lee Beach and flanker Mark Lewis are chosen alongside Wayne O'Connor.
Wing Richard Fussell, another Under-21 Academy player, makes his debut.
Ebbw Vale: Mark Meehan; Nick Wakley, Rhys Shorney, Paul Matthews, Andrew Bevan; Byron Hayward, Gareth Betts; Adam Black, Leyton Phillips, (c) Daminen Pensini, Chay Billen, Peter Sidoli, Will Thomas, Kati Tuiplotu, Tyron Morris
Pontypridd: Gareth Wyatt; Richard Fussell, Jason Lewis, Jon Bryant, Matthew Nutthall; Ceri Sweeney, Gareth Baber; Neil Hennessy, Mefin Davies (capt), Duncan Bell, Dale McIntosh, Robert Sidoli, Mark Lewis, Wayne O'Connor, Lee Beech.
Replacements: Richard Johnston, Neil Jenkins, Paul John, AN Other, Matthew Rees, Brent Cockbain, Kingsley Jones.