The competition kicks-off on the weekend of Saturday, 21 November, with SWALEC Cup winners Neath taking on Bristol Rugby at The Gnoll, Newport hosting Exeter Chiefs at Rodney Parade and the four other Principality Premiership clubs clashing in two mouth-watering Welsh derbies, Pontypridd at home to Cardiff while Llanelli welcome Aberavon to Parc y Scarlets.
In Round two the following weekend, three Welsh teams again have home advantage, Newport hosting Plymouth Albion, Aberavon entertaining London Welsh in a plum tie at the Talbot Athletic Ground and Pontypridd taking on Doncaster Knights. Cardiff, Llanelli and Neath travel to Birmingham & Solihull, Bedford Blues and Nottingham respectively.
Rounds Three, Four and Five take place during the Six Nations period, the first of which takes place on the weekend of 13 February when Wales clubs play Scottish and Irish opposition for the first time, Newport hosting Scotland's National Academy, Neath travelling to Heriots FP and Llanelli hosting Ulster. Pontypridd and Cardiff meanwhile take on English opposition away from home, Pontypridd at Rotherham Titans and Cardiff at Birmingham & Solihull.
Neath take on Munster on the weekend of 27 February while Newport travel to Leinster. Llanelli host Moseley and Cardiff welcome Rotherham Titans to the Arms Park while Pontypridd and Aberavon travel to Ayr and Bedford Blues respectively.
The final round of Pool games takes place on the weekend of 6 March or midweek on March 10 / 11. In a final bid to secure semi-final places, Newport will travel to Penzance to take on Cornish Pirates, Neath host Coventry, Llanelli travel to Richmond to play London Welsh, Aberavon travel to Belfast to challenge Ulster, and Pool D's Pontypridd and Cardiff travel to Birmingham & Solihull and Ayr respectively.
WRU Head of Rugby, Performance and Development Joe Lydon said: "We knew we could expect some high-calibre encounters at the very earliest stages of the competition but it's an added boost for the Welsh clubs to be able to kick-off their British and Irish Cup campaign on Welsh soil.
"The British and Irish Cup is an opportunity for us to develop more players to achieve their full potential and enable them to compete at the very highest level.
"Welsh rugby fans have traditionally savoured the sporting edge delivered by cross border games and this cup will give our Premier Division a fantastic lift onto the next level of competition."
Chris Clarke, chair of the Welsh Premier Division clubs added: "It is a very exciting time for everyone involved in Premiership club rugby. We feel this is a very positive move by the Welsh Rugby Union to get involved in this project and by the clubs who have given it their full support.
"It is a level of competition that has been called for by semi-professional clubs in Wales for some time, and its introduction will help bridge the gap towards professional, Regional rugby in Wales.
"We look forward to seeing this tournament kick-off and grow into something special."
Porthcawl recently received a WRU facilities grant and funding from Natwest RugbyForce in order to give their changing rooms a facelift. This came after receiving £10,000 in a WRU facilities grant last year to tarmac their car park. The improvements have already helped to make the club more accessible, not only for their own members and players but for the whole community.
The Welsh Rugby Union has launched a new, accredited Safeguarding and Protecting Children course - funded by the WRU and delivered in partnership with Sport Wales and the NSPCC - fo rugby club volunteers around Wales.
The SWALEC semi-final draws threw up some mouth-watering clashes in the Cup, Plate and Bowl as the 12 teams aim for the Millennium Stadium Finals Day. All the semi-finals are to be played on the weekend of April 12.
Welsh whistler Rhys Thomas continues to scale the heights of the game as he prepares to be an official in this weekend's Hong Kong Sevens tournament, undoubtedly the showpiece event on the World Series calendar.
Wales International Ian Evans and Wales and Lions legend Scott Quinnell swapped rugby balls for paint pots at Tonna during the RBS 6 Nations. They surprised club players with a special clubhouse makeover to launch NatWest RugbyForce 2014 - a programme developed in partnership with the WRU to make rugby clubs stronger businesses by improving and renovating their facilities with the support of volunteers and the local community.
Fresh from claiming the Bowl honours in Tokyo last Sunday, the Wales Sevens squad have settled into their routine as they prepare for this weekend's Hong Kong tournament where Iolo Evans is aiming high, as WRU TV's Graeme Gillespie discovers.
The Welsh Rugby Union has recently teamed up with Prostate Cymru to help the charity launch its latest campaign to raise awareness of the disease. Members of the Wales squad helped produce a short video and promotional material for the campaign titled 'The Best Defence - is to know the FACTS'.