Gavin Henson's injury jinx has struck Wales again on the eve of their Six Nations title defence.
Injury-plagued Henson was named to start the Wales opener against Scotland tomorrow (Sun) but has pulled out with a calf strain.
British Lion Tom Shanklin replaces Henson in the starting line-up at outside centre with Cardiff Blues team-mate Jamie Roberts switching to inside centre with Andrew Bishop coming onto the bench.
This is the latest set-back for the Wales and Ospreys star who has been dogged by problems both on and off the pitch.
Henson has made just nine starts in three years for Wales since damaging his shoulder playing for the British Lions in 2005.
Groin surgery and suspension hampered 2006 while a year later, the 26-year-old tore cruciate knee ligaments before missing out on the World Cup that year with an Achilles problem.
Henson returned from a broken hand to spearhead last year's Slam success only to sit out the next six months following ankle surgery.
He then withdrew on the eve of the 2008 autumn series after the Achilles problem reared up once again before this latest set-back.
Wales coach Warren Gatland kept his faith in Henson who has been a lucky charm in the Six Nations having never lost in ten championship games when he has started.
Gatland said: "Gavin just felt his calf tightening in training. There is no point making it a major problem that would keep him out for six or eight weeks."
Wales (v Scotland): Lee Byrne; Leigh Halfpenny, Tom Shanklin, Jamie Roberts, Shane Williams; Stephen Jones, Mike Phillips; Gethin Jenkins, Matthew Rees, Adam Jones, Ian Gough, Alun Wyn Jones, Ryan Jones (capt), Andy Powell, Martyn Williams. Replacements: John Yapp, Huw Bennett, Luke Charteris, Dafydd Jones, Dwayne Peel, James Hook, Andrew Bishop.
Angus O'Brien has quickly settled into the Wales Sevens squad after solid performances in Hong Kong and Japan. With two rounds remaining in Glasgow and Twickenham on the World Series, WRU TV's Graeme Gillespie chats to the rising star.
Wales winger Luke Morgan has established himself as one of the deadliest finishers on the Sevens World Series. WRU TV's Graeme Gillespie catches up with him on the eve of this weekend's round in Glasgow.
All roads lead to Cardiff on Sunday for the SSE SWALEC Finals Day at the Millennium Stadium. Cambrian Welfare tackle Ystradgynlais in the Bowl final, Ystrad Rhondda play Newcastle Emlyn in the Plate final while defending champions Pontypridd face Bridgend in the Cup final.
WRU Chief Executive Roger Lewis, Deputy Minister for Culture, Sport and Tourism Ken Skates and WRU Chairman Gareth Davies earlier this week launched a new competition in conjunction with the WRU unveiling its archive room.
Welsh players and management joined Deputy Minister for Sport Ken Skates at the Pierhead Building, Cardiff Bay earlier this week to reveal the Union's pioneering school-club hub initiative has been so successful the project will now almost double the scale of the original project.
The Scarlets, Newport Gwent Dragons, Cardiff Blues and the Ospreys look ahead to Judgement Day III which sees the Blues take on the Ospreys (2.30) and the Dragons tackle the Scarlets (4.45pm) at the Millennium Stadium tomorrow afternoon.
Ystradgynlais and Ynysddu played out a titanic struggle at Taffs Well in the SSE SWALEC Bowl semi-final. At the end of the game neither team could be separated after a 15-15 stalemate but Ystradgynlais go through on try count.
Blues strike first in JD III battle - Newport Gwent Dragons lock Andrew Coombs, WRU referee Dylan Llyr Jones and Cardiff Blues hooker Matthew Rees decide dressing room allocations for Judgement Day III
Wales Under 18 captain Calum Haggett has received a conditional offer to read Biomedical Science at St Anne's College, Oxford. WRU chairman Gareth Davies went to meet Calum and Coleg y Cymoedd Principal Judith Evans to wish him luck in his exams and pass on some of his personal experience.