Carmarthen Quins came within inches of causing an upset against SWALEC Cup holders Neath.
Quins winger Ryan Llewellyn crashed over for a dramatic try in stoppage time to bring the scoreline back to 22-20 in Neath's favour.
But they missed out on a shot at extra-time as Quins outside-half Gareth Cull saw his conversion attempt shave the post.
Centre Luke Ford's try for Neath eight minutes from time proved to be the match winner.
Division One West club Tonmawr also failed to take their chance of an upset, losing 23-16 at home to Premiership Glamorgan Wanderers.
With the game locked at 16-16, Wanderers capitalised on the sin-binning of hooker Rhys Lawrence as winger Jamie Jones scored the game winning try with ten minutes left.
Llantwit Fardre, the lowest ranked team left in the competition, could not fashion a shock as they were hammered 74-0 at Aberavon.
The Division Three South East leaders, who had been unbeaten in 18 games, were sent crashing out by the Premiership side who scored 11 tries, including two each for centre Richard Thomas and No8 Rory Gallacher.
Caerphilly are now the only non-Premiership club remaining in the Swalec Cup after they won an all-Division One East tie at Rumney 17-12.
Outside-half Dan Ellis scored the Cheesemen's only try and kicked the rest of their points.
In three all-Premiership clashes, Cross Keys edged out Pontypridd 27-26, Swansea won at Ebbw Vale 23-13 and Newport beat Llandovery 38-18.
The WRU has launched a campaign to create a long term legacy for Welsh club rugby by highlighting the advantages of volunteering. Rhian Edwards, a volunteer at Seven Sisters, has enjoyed many benefits of her volunteering at a grassroots rugby club including being part of the Rugby World Cup volunteer workforce after being nominated by the WRU - and the WRU is asking for more people to develop their 'Welsh rugby roots'.
Wales head coach Warren Gatland and captain Sam Warburton say their first prioirty on Sunday in the opening game of the World Cup is to win against Uruguay and not get overly concerned with points difference.
With only days to go until the biggest rugby competition in the world begins, rugby fans visiting Cardiff this autumn will be able to enjoy a special display at National Museum Cardiff as part of the celebrations surrounding the Rugby World Cup.
Geraint John has taken up the new role of WRU elite coach development manager having arrived in Wales last week. WRU TV caught up with him at the WRU rugby department's strategy day at the Millennium Stadium.