Carmarthen Quins came within inches of causing an upset against SWALEC Cup holders Neath.
Quins winger Ryan Llewellyn crashed over for a dramatic try in stoppage time to bring the scoreline back to 22-20 in Neath's favour.
But they missed out on a shot at extra-time as Quins outside-half Gareth Cull saw his conversion attempt shave the post.
Centre Luke Ford's try for Neath eight minutes from time proved to be the match winner.
Division One West club Tonmawr also failed to take their chance of an upset, losing 23-16 at home to Premiership Glamorgan Wanderers.
With the game locked at 16-16, Wanderers capitalised on the sin-binning of hooker Rhys Lawrence as winger Jamie Jones scored the game winning try with ten minutes left.
Llantwit Fardre, the lowest ranked team left in the competition, could not fashion a shock as they were hammered 74-0 at Aberavon.
The Division Three South East leaders, who had been unbeaten in 18 games, were sent crashing out by the Premiership side who scored 11 tries, including two each for centre Richard Thomas and No8 Rory Gallacher.
Caerphilly are now the only non-Premiership club remaining in the Swalec Cup after they won an all-Division One East tie at Rumney 17-12.
Outside-half Dan Ellis scored the Cheesemen's only try and kicked the rest of their points.
In three all-Premiership clashes, Cross Keys edged out Pontypridd 27-26, Swansea won at Ebbw Vale 23-13 and Newport beat Llandovery 38-18.
WRU TV were on hand at the launch of a major new commercial deal with WRU and Mercedes-Benz South Wales (part of the Sinclair Group), which sees the family company become an official supplier to the Welsh Rugby Union
On the back of the recent Women's Rugby World Cup, the WRU has launched a revitalised Women's and Girls domestic seasonal structure, and the future is looking bright.
Go to www.wru.co.uk/tryourgame for more information
Roger Lewis talks to WRU TV at the announcement of a new £60 million Rugby Services Agreement (RSA) which provides a new and positive contractual relationship between the WRU and its four Regions for the next six years has been agreed.
The Welsh Rugby Union has announced a major new sponsorship deal with Gullivers Sports Travel which will make the UK's leading, and longest established, multi-sport tour operator, an Official Supplier for the rest of the decade.
Having taken part in seven World Cups as a player and coach, Liza Burgess hopes to go out in style this afternoon when Wales take on Australia in the Play-off for seventh and eighth place in the Women's Rugby World Cup in Paris.