Gavin Henson has been withdrawn from the Wales squad which travels to Scotland this afternoon (Friday, 6 February) in preparation for the opening match of their RBS 6 Nations title defence at Murrayfield on Sunday.
The Ospreys centre has failed to recover from a calf strain and is to be replaced in the starting line-up by Tom Shanklin, who slots in at outside centre with his Cardiff Blues team-mate Jamie Roberts reverting to the number 12 position. Another Ospreys centre, Andrew Bishop, takes up the spot vacated by Shanklin on the bench.
Henson's injury will be re-assessed next week and no further information will be available until that time.
Warren Gatland and Sam Warburton look ahead to this week's crunch RBS 6 Nations tie against France, where the Wales skipper in particular is keen to make his mark, as Paris has proved a bleak place for him in the past.
Following their historic win over England, Wales Under 20 suffered a narrow, 36-34 loss to their Scottish counterparts last weekend, despite outscoring them by five tries to three. Watch the match highlights and reaction.
WRU TV go behind the scenes with the Wales squad as they put the final touches in place ahead of the clash against Scotland at Murrayfield. Follow the squad on their captain's run, the kickers visit to Murrayfield and Neil Jenkins' press conference