Neath entertain Aberavon at The Gnoll in the traditional Easter Monday fixture (KO 2.30pm) where the Wizards will be hoping to continue their recent impressive form.
Due to injuries, the Welsh All Blacks have named a preliminary squad from which the team will be finalised following training today.
Included is try-scoring hooker Andy Littlehales, short of game time recently, who will help out Cross Keys on Saturday following an appeal from the Gwent club who have been plunged into a hooking crisis.
Neath's Director of Rugby, Rowland Phillips, said: "Normally by now we would have a fair idea of our squad and starting line-up. However, given an unprecedented crop of injuries, we are some way off that. Weekend training will consolidate our preparations for what is one of the most keenly anticipated games in the calendar.
"Aberavon are the 'form team' of Welsh rugby with games in hand in the League and are also looking forward to their Cup semi-final next weekend. We will be looking for a massive improvement after the Ebbw Vale game."
Spectators are asked to arrive early to avoid congestion at the gates for a fixture that traditionally attracts the Premiership's biggest gate of the season.
As the countdown continues for RWC2015, Tournament Chief Executive Debbie Jevans visited the Millennium Stadium to discuss preparations for the eight matches and reveal the positive news that 100,000 tickets for games at the home of Welsh rugby have sold in the last seven days.
Jason Harries is targeting a first win on the World Series circuit this season with Wales. The series returns to action this weekend in Dubai where Harries is part of a team hoping to build from its efforts in round one in October.
Wales skipper Jevon Groves says his side have addressed a few points from Gold Coast and aim to 'hit the ground running' in the next two rounds of the World Series, kicking off with this weekend in Dubai before heading off to South Africa next week.
Wales Sevens manager Steff Thomas is hopeful his side can build from a quarter-final spot in the opening round of the World Series in Australia when his side take part in the forthcoming double header in Dubai and South Africa.