Neath entertain Aberavon at The Gnoll in the traditional Easter Monday fixture (KO 2.30pm) where the Wizards will be hoping to continue their recent impressive form.
Due to injuries, the Welsh All Blacks have named a preliminary squad from which the team will be finalised following training today.
Included is try-scoring hooker Andy Littlehales, short of game time recently, who will help out Cross Keys on Saturday following an appeal from the Gwent club who have been plunged into a hooking crisis.
Neath's Director of Rugby, Rowland Phillips, said: "Normally by now we would have a fair idea of our squad and starting line-up. However, given an unprecedented crop of injuries, we are some way off that. Weekend training will consolidate our preparations for what is one of the most keenly anticipated games in the calendar.
"Aberavon are the 'form team' of Welsh rugby with games in hand in the League and are also looking forward to their Cup semi-final next weekend. We will be looking for a massive improvement after the Ebbw Vale game."
Spectators are asked to arrive early to avoid congestion at the gates for a fixture that traditionally attracts the Premiership's biggest gate of the season.
Wales Head Coach Rob Howley talks to WRU TV's Sebastian Barrett about the 36-man squad he has just named for the forthcoming Under Armour series, which includes two uncapped players, Ospreys duo Sam Davies and Rory Thornton.
Head coach Rowland Phillips is deligthed he can now call BT Sport Cardiff Arms Park home for his Wales Women's side, who launch their international season next month with games against Scotland and UK Armed Forces in the heart of the capital city.
Wales Sevens star Sam Cross has put his home town club of Brynmawr on the map after winning a silver medal at the Rio Olympics with Team GB. His club have now honoured him by naming their players bar after him, as WRU TV discovered at the official launch, recently.
One of the newest members of the Principality Premiership, Bargoed admit it's proving to be a steep learning curve at the highest level, but are determined to become a force to be reckoned with. WRU TV visited the club last weekend when they took on Llanelli.
Table-topping Aberavon travel to north Wales to tackle RGC 1404 as both teams defend unbeaten starts to the season in the Principality Premiership. WRU TV's Graeme Gillespie visited the Wizards to see how their preparations were going for the game of the weekend.
The Half a Game initiative is currently sweeping across Wales and proving a major success. The scheme aims to give every young player at least half a game every weekend. WRU TV recently visited a festival in Narberth where clubs have fully embraced the initiative.
Both Bargoed and Swansea were seeking their first win of the Principality Premiership season this afternoon. It proved a fruitful day for the hosts - not only did they win, but Bargoed claimed a try bonus point.
Cardiff managed to keep their unbeaten record at home intact, but only just as Bridgend made them work extremely hard before the Blue and Blacks secured a hard fought Principality Premiership win at the BT Sport Arms Park last night.
Former Wales back row Andy Powell gives a guided tour of The Wern, home of Merthyr RFC, who are determined to prove a lot of people wrong and make their mark in their first season in the Principality Premiership.