Neath entertain Aberavon at The Gnoll in the traditional Easter Monday fixture (KO 2.30pm) where the Wizards will be hoping to continue their recent impressive form.
Due to injuries, the Welsh All Blacks have named a preliminary squad from which the team will be finalised following training today.
Included is try-scoring hooker Andy Littlehales, short of game time recently, who will help out Cross Keys on Saturday following an appeal from the Gwent club who have been plunged into a hooking crisis.
Neath's Director of Rugby, Rowland Phillips, said: "Normally by now we would have a fair idea of our squad and starting line-up. However, given an unprecedented crop of injuries, we are some way off that. Weekend training will consolidate our preparations for what is one of the most keenly anticipated games in the calendar.
"Aberavon are the 'form team' of Welsh rugby with games in hand in the League and are also looking forward to their Cup semi-final next weekend. We will be looking for a massive improvement after the Ebbw Vale game."
Spectators are asked to arrive early to avoid congestion at the gates for a fixture that traditionally attracts the Premiership's biggest gate of the season.
The WRU has teamed up with Crawshay's to tour Georgia in June. The side, which will be called the Crawshays WRU President's XV, will play Emerging Georgia twice, in a tour which supports the Welsh Government's efforts to grow relations between the two countries.
Wales Sevens are looking to re-group after a disappointing tournament last time out in South Africa. The next double leg in New Zealand and Las Vegas offers Gareth Williams a chance to redeem themselves.
Wales Women's head coach Rhys Edwards was at Llandovery to see the conclusion of an entertaining Women's Regional championship where any one of three teams were in contention for title glory on the last day of action.