Neath entertain Aberavon at The Gnoll in the traditional Easter Monday fixture (KO 2.30pm) where the Wizards will be hoping to continue their recent impressive form.
Due to injuries, the Welsh All Blacks have named a preliminary squad from which the team will be finalised following training today.
Included is try-scoring hooker Andy Littlehales, short of game time recently, who will help out Cross Keys on Saturday following an appeal from the Gwent club who have been plunged into a hooking crisis.
Neath's Director of Rugby, Rowland Phillips, said: "Normally by now we would have a fair idea of our squad and starting line-up. However, given an unprecedented crop of injuries, we are some way off that. Weekend training will consolidate our preparations for what is one of the most keenly anticipated games in the calendar.
"Aberavon are the 'form team' of Welsh rugby with games in hand in the League and are also looking forward to their Cup semi-final next weekend. We will be looking for a massive improvement after the Ebbw Vale game."
Spectators are asked to arrive early to avoid congestion at the gates for a fixture that traditionally attracts the Premiership's biggest gate of the season.
Beating Merthyr has boosted Carmarthen Quins hopes of reaching a top eight spot in the Principality Premiership. Quins captain Haydn Pugh is delighted with his team's progress and is determined that everyone from the Under 6s through to the senior team, enjoys the ride.
When the Wales squad were asked to nominate individuals who played a big part in their early playing days, Wales and Dragons full back and wing Hallam Amos thought of his former Monmouth School rugby coach John Bevan.
Sam Cross and Luke Treharne have been named as co-captains of the Wales Sevens side as head coach Gareth Williams names his 12-man squad to play in the first leg of the HSBC World Series in Dubai next weekend.
Bedwas head coach Steve Law and players Nicky Griffiths and Alun Rees extol the virtues of the close knit club as they prepare to host third place RGC 1404 - who are one place head of them on the Principality Premiership points table - on Saturday.
Many of the Wales squad have said Diolch (thank you) to someone who played an important part in their early playing days by nominating them to be invited to the Wales v South Africa match. One person, Gowerton Comprehensive geography teacher Mr Dean Mason was nominated by two of his former pupils, Dan Biggar and Sam Davies.
The second WRU disability rugby pilot has been delivered, this time in Caerphilly schools, culminating in a festival at the Caerphilly Centre of Sporting Excellence, Ystrad Mynach tomorrow. Plans are in place to set up a Disability Rugby Club in Newbridge to provide long-term playing opportunities.
WRU TV: Hear from inside the Wales camp as Neil Jenkins discusses this weekend's clash with South Africa and how the squad are looking to put in a strong performance to round of the 2016 Under Armour Series