Young centre Jonathan Davies has a new centre partner in Rob Higgitt.
New Wales squad members Jonathan Davies and Rob McCusker are due to start as the Scarlets travel to the Cardiff Blues on Wednesday (kick-off 19:35).
Davies is named at outside centre to form a midfield partnership with Rob Higgitt while McCusker begins as openside flanker with experienced internationals Dafydd Jones and David Lyons completing the backrow.
Davies, aged 21, and McCusker, 23, have both been named in this summer's Wales squad which will tour North America. Jones will be joined by Scarlets teammates Mark Jones and Josh Turnbull.
Wing Jones misses the Arms Park Magners League clash with a knee injury. Back from injury in his place is wing Darren Daniel. Scarlets Lions Matthew Rees and Stephen Jones start on the bench and Simon Easterby returns as a replacement following surgery. Easterby's captaincy role is taken for the night by Lyons.
Scarlets head coach Nigel Davies said: "I'm very pleased for the Scarlets who have been named in the new Wales squad, particularly for the first-timers Josh, Rob and Jon. This season we've talked a lot about the development of our younger players and them having to stand up for us and it's been great that they've responded so well.
"Between them all they've played a lot of games and as a result they've made it into the national squad."
For McCusker there was more reason to celebrate this week as he signed a two-year extension to his Scarlets contract. Jonathan Davies signed an extension in March.
Davies said: "Rob has been around our set-up for a few years and this season has shown new maturity, has developed a genuine edge to his game, has contributed well to the group and now understands the game really well. He's somebody with a very bright future."
An Arms Park win is important to the Scarlets as they fight to secure automatic Heineken Cup qualification for next season. Their only game after this is on Saturday at home to Ulster.
Davies said: "We go to Cardiff with a strategy and with a strong, competitive 22. We should show a real hunger and desire because we've got everything to play for. "
Having secured a win against the Dragons last Wednesday the Blues will be looking to notch up another victory over Welsh rivals when they take on the Scarlets.
Speaking ahead of the match coach David Young said, "The Scarlets are fighting for their lives with the Dragons to avoid the play off match in Italy and I imagine they'll come here hoping that we'll roll over because the job is done for us. We never want to lose any games at home and especially to our Welsh rivals and I expect it to be another hotly contested Welsh derby."
Teams: Blues 15 Ben Blair 14 Richard Mustoe 13 Jamie Robinson 12 Gareth Thomas 11 Chris Czekaj 10 Ceri Sweeney 9 Richie Rees 8 Maama Molitika 7 Robin Sowden-Taylor (capt) 6 Ben White 5 Deiniol Jones 4 Bradley Davies 3 Faao Filise
2 Rhys Thomas 1 John Yapp
Replacements: 16 Gary Powell 17 Ross Johnston 18 James Down 19 Scott Morgan 20 Darren Allinson 21 Dai Flanagan 22 Nicky Robinson
Scarlets: 15 Daniel Evans, 14 Darren Daniel, 13 Rob Higgitt, 12 Jon Davies, 11 Lee Williams, 10 Rhys Priestland, 9 Gavin Cattle, 1 Phil John, 2 Ken Owens, 3 Deacon Manu, 4 Lou Reed, 5 Dominic Day, 6 Dafydd Jones, 7 Rob McCusker, 8 David Lyons (c). Reps - 16 Iestyn Thomas, 17 Matthew Rees, 18 Aaron Shingler, 19 Simon Easterby, 20 Martin Roberts, 21 Stephen Jones, 22 Ceiron Thomas.
Principality Stadium will host the UEFA Champions League Final in six weeks' time. WRU chairman Gareth Davies, Football Association of Wales chief executive Jonathan Ford and Ambassador Ian Rush joined young sports fans at the trophy arrival at the venue to celebrate the magnitude of the event on Saturday 3rd June (kick-off 19.45).
British and Irish Lions captain Sam Warburton is looking forward to bringing together players from Ireland, Scotland, England and Wales for the biggest challenge of their careers - a series against world champions, New Zealand.
For the fifth year running, Wales referee Nigel Owens will be in charge of proceedings at Judgement Day V at Principality Stadium. It promises to be 'extra special' for the Wales' favourite ref, as he will be making his 150th appearance in the league.
There will be no shortage of inside knowledge from Bowl Finalists Caerphilly and Amman United when they face each other on Sunday at National Finals Day. Caerphilly hooker Rhys Cleverly knows the Principality Stadium pitch better than most as a matchday groundsman, while Amman United can look to Wales' record try scorer Shane Williams for some helpful advice.
Two hundred and 40 teams competed in the inaugural Urdd WRU 7s held at Pencoed last week with Welsh internationals Steff Andrews and Jasmine Joyce impressed with the talent on display, as was Urdd chief executive, Sioned Hughes.
The countdown is on for Judgement Day V as tickets for the big day at Principality Stadium soar through the 50,000 mark. Players and coaches alike are bursting at the seams to play in the double header with Dragons coach Kingsley Jones claiming there is a 'real buzz' about the event.
WRU TV went behind the scenes when the four regions got together to test their skill set for the BBC's Scrum V Live rugby show, at the WRU National Centre of Excellene in the build up to Judgement Day V. Blues' Matthew Morgan was one of the stars of the show while the Dragons' Cory Hill proved a surprise package...the full set of results will be revealed on tv screens on matchday
Wales assistant coach Richie Pugh is confident his side can cause a few headaches in the Hong Kong Sevens this weekend. In a tough group, Wales kick off their campaign against New Zealand on Friday before playing Japan and Fiji, who are chasing their third consecutive Hong Kong title, on Saturday.
Bedwas had to overcome a stubborn Carmarthen Quins side before winning the Foster's Challenge Cup final in Bridgend with a 23-18 victory. Bedwas captain Nicky Griffiths pays tribute to his side who have claimed the club's first piece of silverware in the modern era.
Team coach Brett Davey is aiming to keep his unbeaten run in cup finals at Principality Stadium intact when his side take on Amman United in the WRU Bowl final, after he guided Caerphilly to a 20-14 win against Cilfynydd in the semi-finals.
Penallta are hoping to go one step further than last season when falling to Bedlinog in the WRU Plate Final. After a titanic struggle against Nant Conwy, they have given themselves a great chance, after a hard fought 18-13 semi-final victory.