Two new caps will make their international Sevens debut over the next 10 days - Cornish Pirates pivot Rhys Jones, son of Sale Sharks Director of Rugby Kingsley, and Pontypool scrum half Tom Edwards.
Will Harries, Ifan Evans, Rhys Shellard and Jevon Groves have all gained match time on the IRB Sevens circuit this season and will continue their development at the UK tournaments.
Wales Sevens head coach Paul John said, "It has been difficult to get back into Sevens training at the end of a long season for the players and coaches. However, we have trained hard over the last couple of weeks and we will do everything we can to be competitive at these two tournaments.
"We have a tough Pool at both events, starting with hot tournament favourites South Africa, Australia and Germany at Twickenham on the weekend. South Africa are series leaders and hot favourites for the title, while we haven't beaten either South Africa or Australia all season and Germany are an unknown to us.
"We will have to be at our best to get out of that Pool and gain some important tournament points to end the season on a high. We know we are capable of beating anyone on our day, as we did at the World Cup and our defence will have to be as water-tight as in Dubai if we are going to make it to the last eight.
"It is great that some of our young players can benefit from playing with our more seasoned internationals on these two tournaments, I'm sure they will gain a great deal out of the experience."
Wales Sevens squad for London and Edinburgh Sevens:
Lee Beach (capt, Neath), James Merriman (unattached), Rhys Shellard (Cardiff), Jevon Groves (Cross Keys), Craig Hill (Newport, LONDON ONLY), Tom Edwards (Pontypool, LONDON ONLY), Aled Thomas (London Welsh), Tom Isaacs (Newport), Rhys Jones (Cornish Pirates), Tal Selley (Dragons), Will Harries (Northampton Saints), Ifan Evans (Llandovery), Jimmy Norris (Bedwas / Dragons, EDINBURGH ONLY), Lee Williams (Scarlets, EDINBURGH ONLY)