Glamorgan Wanderers are forced into two changes from the side that beat Newport for the trip to Carmarthen.
Tom Evans and Mike Grimes are out of the pack and in come Richard Thomas and Lee Highgate.
On the bench Matt Trowbridge returns after missing two games through injury and scrum half Rhys Dyer gets a place in the squad for the first time this season.
Dan Fish, who has impressed everyone this season, continues at fullback and he has been rewarded for his efforts with a place at the Blues academy.
Glamorgan Wanderers: 15. Dan Fish 14. Rory Budina 13. Charlie Johnson 12. Robin Lock 11. Ryan Healey 10. Scott Sneddon 9. Harry Trelawny; 1. Nathan Trevett 2. Ieuan Davies 3. Scott Andrews (capt) 4. Richard Thomas 5. Gareth Knight 6. Lee Highgate 7. Ben Rose 8. Josh Navidi
Replacementa: 16. Ieuan Dobbs 17. Mark O'Leary 18. Dan Partridge 19. Carl Kimber 20. Lee Highgate 21. Steve Cullen 22. Rhys Dyer
Despite drawing with Ireland in the opening round of the RBS 6 Nations, Wales defence coach Shaun Edwards believes the championship 'is still in our hands' as he prepares his side to face Scotland at Principality Stadium tomorrow.
Meet the members of the WRU's inaugural Youth Board - after an online selection process which saw a host of high calibre candidates submit video applications the WRU has made its first 15 appointments.The board is made up of individuals aged between 16 and 21, and will meet for the first time at Principality Stadium on Monday 15th February.
The Wales Women's team headed to Dare Valley Country Park on a team bonding exercise as the entire squad got together for the very first time in preparation for this season's Six Nations championship which kicks off on Saturday with a clash against defending champions Ireland, in Donnybrook.
Wales Head Coach Warren Gatland discusses his team selection for the opening round of the RBS 6 Nations where he leads his side against Ireland, on Sunday. As WRU TV's Luke Brodley discovers, Gatland is fully aware of the challenges the defending champions pose