Glamorgan Wanderers are forced into two changes from the side that beat Newport for the trip to Carmarthen.
Tom Evans and Mike Grimes are out of the pack and in come Richard Thomas and Lee Highgate.
On the bench Matt Trowbridge returns after missing two games through injury and scrum half Rhys Dyer gets a place in the squad for the first time this season.
Dan Fish, who has impressed everyone this season, continues at fullback and he has been rewarded for his efforts with a place at the Blues academy.
Glamorgan Wanderers: 15. Dan Fish 14. Rory Budina 13. Charlie Johnson 12. Robin Lock 11. Ryan Healey 10. Scott Sneddon 9. Harry Trelawny; 1. Nathan Trevett 2. Ieuan Davies 3. Scott Andrews (capt) 4. Richard Thomas 5. Gareth Knight 6. Lee Highgate 7. Ben Rose 8. Josh Navidi
Replacementa: 16. Ieuan Dobbs 17. Mark O'Leary 18. Dan Partridge 19. Carl Kimber 20. Lee Highgate 21. Steve Cullen 22. Rhys Dyer
As the countdown continues for RWC2015, Tournament Chief Executive Debbie Jevans visited the Millennium Stadium to discuss preparations for the eight matches and reveal the positive news that 100,000 tickets for games at the home of Welsh rugby have sold in the last seven days.
Jason Harries is targeting a first win on the World Series circuit this season with Wales. The series returns to action this weekend in Dubai where Harries is part of a team hoping to build from its efforts in round one in October.
Wales skipper Jevon Groves says his side have addressed a few points from Gold Coast and aim to 'hit the ground running' in the next two rounds of the World Series, kicking off with this weekend in Dubai before heading off to South Africa next week.
Wales Sevens manager Steff Thomas is hopeful his side can build from a quarter-final spot in the opening round of the World Series in Australia when his side take part in the forthcoming double header in Dubai and South Africa.