Cardiff Blues could be without influential back row forward Maama Molitika for the whole of their Pool 5 Heineken Cup campaign.
The Tongan international damaged his pectoral muscle in the recent win over the Scarlets and is expected to be out of action for up to four months. The injury means the Blues could kick-off their European season without a complete back row unit.
Already ruled out until December is Wales and British & Irish Lions flanker Martyn Williams, who underwent shoulder surgery after returning from South Africa this summer, while No 8 Xavier Rush is struggling with a dislocated finger. Rush was another injury victim in the win over the Scarlets.
The Blues launch their Heineken Cup season with a home game against the Harlequins next week and then have to travel to Sale Sharks in Round 2. They then face Toulouse in back to back matches in December.
Blues coach Dai Young, who led his side to the semi-finals last season, is also sweating on the availability of Lions centre Jamie Roberts for the game against the Quins. He suffered a soft tisssue injury to his neck in the game against the Scarlets and has been sidelined for 7-10 days.
On the positive side, Young looks set to have Wales wing Tom James back in harness in time for the big Euro kick-off. James, who scored the dramatic try in the semi-final at the Millennium Stadium last season that took the game against Leicester Tigers into extra-time and then penalties, underwent surgery during the summer.
Wales reached their first semi-final since 2013 in the opening round of this season's HSBC World Rugby Sevens Series in Dubai. WRU TV's Graeme Gillespie recaps on what proved to be an eventful tournament
Wales and Ospreys back row James King, who came through the North Wales age grade system, nominated North Wales Regional Community Rugby Manager Marc Roberts, in the WRU's 'Diolch' initiative where squad players thanked those who played a part in their rise to the top.
Beating Merthyr has boosted Carmarthen Quins hopes of reaching a top eight spot in the Principality Premiership. Quins captain Haydn Pugh is delighted with his team's progress and is determined that everyone from the Under 6s through to the senior team, enjoys the ride.
When the Wales squad were asked to nominate individuals who played a big part in their early playing days, Wales and Dragons full back and wing Hallam Amos thought of his former Monmouth School rugby coach John Bevan.
Sam Cross and Luke Treharne have been named as co-captains of the Wales Sevens side as head coach Gareth Williams names his 12-man squad to play in the first leg of the HSBC World Series in Dubai next weekend.
Bedwas head coach Steve Law and players Nicky Griffiths and Alun Rees extol the virtues of the close knit club as they prepare to host third place RGC 1404 - who are one place head of them on the Principality Premiership points table - on Saturday.
Many of the Wales squad have said Diolch (thank you) to someone who played an important part in their early playing days by nominating them to be invited to the Wales v South Africa match. One person, Gowerton Comprehensive geography teacher Mr Dean Mason was nominated by two of his former pupils, Dan Biggar and Sam Davies.
The second WRU disability rugby pilot has been delivered, this time in Caerphilly schools, culminating in a festival at the Caerphilly Centre of Sporting Excellence, Ystrad Mynach tomorrow. Plans are in place to set up a Disability Rugby Club in Newbridge to provide long-term playing opportunities.
WRU TV: Hear from inside the Wales camp as Neil Jenkins discusses this weekend's clash with South Africa and how the squad are looking to put in a strong performance to round of the 2016 Under Armour Series