Cardiff Blues could be without influential back row forward Maama Molitika for the whole of their Pool 5 Heineken Cup campaign.
The Tongan international damaged his pectoral muscle in the recent win over the Scarlets and is expected to be out of action for up to four months. The injury means the Blues could kick-off their European season without a complete back row unit.
Already ruled out until December is Wales and British & Irish Lions flanker Martyn Williams, who underwent shoulder surgery after returning from South Africa this summer, while No 8 Xavier Rush is struggling with a dislocated finger. Rush was another injury victim in the win over the Scarlets.
The Blues launch their Heineken Cup season with a home game against the Harlequins next week and then have to travel to Sale Sharks in Round 2. They then face Toulouse in back to back matches in December.
Blues coach Dai Young, who led his side to the semi-finals last season, is also sweating on the availability of Lions centre Jamie Roberts for the game against the Quins. He suffered a soft tisssue injury to his neck in the game against the Scarlets and has been sidelined for 7-10 days.
On the positive side, Young looks set to have Wales wing Tom James back in harness in time for the big Euro kick-off. James, who scored the dramatic try in the semi-final at the Millennium Stadium last season that took the game against Leicester Tigers into extra-time and then penalties, underwent surgery during the summer.
Young referee Ben Breakspear is making rapid strides as a referee. In just over a year he has gone from officiating a college game to being a touchline official during last weekend's RBS 6 Nations clash between Wales and Ireland at Principality Stadium.
Grand Slams, Triple Crowns and British and Irish Lions tours - Sir Gareth Edwards did it all. But what are his favourite moments in what was an amazing career? WRU TV finds out - along with his favourite players of today in the third and final instalment of our series with the greatest rugby player ever.
JPR Williams, Gerald Davies and Mervyn Davies were among those in the Welsh ranks when Sir Gareth Edwards began his international career against France nearly 50 years ago, but who was the player who took the young scrum half under their wing?
Wales head coach Rob Howley and captain Alun Wyn Jones are expecting a physical battle against France on Saturday but both are hoping for another impact from the bench as the men in red chase a top-four world ranking.
It's nearly 50 years since the great Sir Gareth Edwards made his debut as a youngster for Wales against France in Stade Colombes. In the first of a series, WRU TV discovers he pocketed a 'special momento' from the game - something he still has today.
This week, Wales squad players Sam Warburton, Jonathan Davies and Ken Owens took time out to support Operation Net Safe, a joint initiative by the four Welsh police forces to tackle child sexual abuse. The forces are working with the Lucy Faithfull Foundation, the only UK-wide child protection charity dedicated solely to reducing the risk of children being sexually abused, on a campaign called Stop it Now!