The Wales Women's side travel to Mira for Sunday's RBS 6 Nations clash determined to make amends for their loss against France two weeks ago.
Wales coach Jason Lewis says the players owe themselves a big performance after the 27-5 defeat in Montauban where the visiting side were made to play second fiddle to a strong French outfit.
"We were always going to make changes for the Italy game but the changes are not related to the loss to France," explained Lewis. "The players have to show strength of character to bounce back. Our goals are still the same as we want to qualify for the World Cup," he added.
The changes include Naomi Thomas moving to full-back from fly-half, allowing the talented Awen Thomas to slot into the No 10 shirt while Pontyclun scrum half Laura Prosser gets her first Six Nations start of the season.
Gemma Hallett goes into the engine room in the second row while Claire Horgan gets the nod on the tighthead side of the scrum while Catrin Edwards has recovered from a broken bone in her foot to start from the bench.
Wales 15 Naomi Thomas (Bristol)
14 Non Evans (Cardiff Quins)
13 Clare Flowers (Bristol - Vice-captain)
12 Rachel Poolman (UWIC)
11 Lou Rickard (Woodbridge)
10 Awen Thomas (Cardiff Quins)
9 Laura Prosser (Pontyclun)
1 Hannah Roberts (UWIC)
2 Rhian Bowden (UWIC)
3 Claire Horgan (Saracens)
4 Gemma Hallett (Pontyclun)
5 Rachel Taylor (Cardiff Quins)
6 Catrina Nicholas (Cardiff Quins)
7 Jamie Kift (Bristol)
8 Mellissa Berry (Bristol - Captain)
As the countdown continues for RWC2015, Tournament Chief Executive Debbie Jevans visited the Millennium Stadium to discuss preparations for the eight matches and reveal the positive news that 100,000 tickets for games at the home of Welsh rugby have sold in the last seven days.
Jason Harries is targeting a first win on the World Series circuit this season with Wales. The series returns to action this weekend in Dubai where Harries is part of a team hoping to build from its efforts in round one in October.
Wales skipper Jevon Groves says his side have addressed a few points from Gold Coast and aim to 'hit the ground running' in the next two rounds of the World Series, kicking off with this weekend in Dubai before heading off to South Africa next week.
Wales Sevens manager Steff Thomas is hopeful his side can build from a quarter-final spot in the opening round of the World Series in Australia when his side take part in the forthcoming double header in Dubai and South Africa.