The Wales Women's side travel to Mira for Sunday's RBS 6 Nations clash determined to make amends for their loss against France two weeks ago.
Wales coach Jason Lewis says the players owe themselves a big performance after the 27-5 defeat in Montauban where the visiting side were made to play second fiddle to a strong French outfit.
"We were always going to make changes for the Italy game but the changes are not related to the loss to France," explained Lewis. "The players have to show strength of character to bounce back. Our goals are still the same as we want to qualify for the World Cup," he added.
The changes include Naomi Thomas moving to full-back from fly-half, allowing the talented Awen Thomas to slot into the No 10 shirt while Pontyclun scrum half Laura Prosser gets her first Six Nations start of the season.
Gemma Hallett goes into the engine room in the second row while Claire Horgan gets the nod on the tighthead side of the scrum while Catrin Edwards has recovered from a broken bone in her foot to start from the bench.
Wales 15 Naomi Thomas (Bristol)
14 Non Evans (Cardiff Quins)
13 Clare Flowers (Bristol - Vice-captain)
12 Rachel Poolman (UWIC)
11 Lou Rickard (Woodbridge)
10 Awen Thomas (Cardiff Quins)
9 Laura Prosser (Pontyclun)
1 Hannah Roberts (UWIC)
2 Rhian Bowden (UWIC)
3 Claire Horgan (Saracens)
4 Gemma Hallett (Pontyclun)
5 Rachel Taylor (Cardiff Quins)
6 Catrina Nicholas (Cardiff Quins)
7 Jamie Kift (Bristol)
8 Mellissa Berry (Bristol - Captain)
Wales reached their first semi-final since 2013 in the opening round of this season's HSBC World Rugby Sevens Series in Dubai. WRU TV's Graeme Gillespie recaps on what proved to be an eventful tournament
Wales and Ospreys back row James King, who came through the North Wales age grade system, nominated North Wales Regional Community Rugby Manager Marc Roberts, in the WRU's 'Diolch' initiative where squad players thanked those who played a part in their rise to the top.
Beating Merthyr has boosted Carmarthen Quins hopes of reaching a top eight spot in the Principality Premiership. Quins captain Haydn Pugh is delighted with his team's progress and is determined that everyone from the Under 6s through to the senior team, enjoys the ride.
When the Wales squad were asked to nominate individuals who played a big part in their early playing days, Wales and Dragons full back and wing Hallam Amos thought of his former Monmouth School rugby coach John Bevan.
Sam Cross and Luke Treharne have been named as co-captains of the Wales Sevens side as head coach Gareth Williams names his 12-man squad to play in the first leg of the HSBC World Series in Dubai next weekend.
Bedwas head coach Steve Law and players Nicky Griffiths and Alun Rees extol the virtues of the close knit club as they prepare to host third place RGC 1404 - who are one place head of them on the Principality Premiership points table - on Saturday.
Many of the Wales squad have said Diolch (thank you) to someone who played an important part in their early playing days by nominating them to be invited to the Wales v South Africa match. One person, Gowerton Comprehensive geography teacher Mr Dean Mason was nominated by two of his former pupils, Dan Biggar and Sam Davies.
The second WRU disability rugby pilot has been delivered, this time in Caerphilly schools, culminating in a festival at the Caerphilly Centre of Sporting Excellence, Ystrad Mynach tomorrow. Plans are in place to set up a Disability Rugby Club in Newbridge to provide long-term playing opportunities.
WRU TV: Hear from inside the Wales camp as Neil Jenkins discusses this weekend's clash with South Africa and how the squad are looking to put in a strong performance to round of the 2016 Under Armour Series