Italy coach Nick Mallett has made two changes to his side after losing the first three matches in this season's RBS Six Nations.
Now his team face defending champions Wales in Saturday's RBS Six Nations game at Rome's Stadio Flaminio, desperate for a win, or even a try. Italy have not crossed the whitewash since a late score in Round 1 against a tiring England team who had already secured victory
But Mallett has not pressed panic button and shown faith with the majority of the side that lost 26-6 to Scotland in Edinburgh last time out.
to Leicester prop Martin Castrogiavanni is dropped to the bench, Gloucester's Carlos Nieto starting at tight-head.
Overmach Parma full-back Giulio Rubini, 21, is given a first start on the wing, Mirco Bergamasco moving back to centre with Gonzalo Garcia missing out. Uncapped Roberto Quartaroli is also brought onto the bench.
Rubini won his first cap as a replacement in last month's 26-6 defeat to Scotland, the Murrayfield loss having followed earlier reversals to England and Ireland.
Azzurri full-back Andrea Masi was last week ruled out of the Wales game because of injury. Masi, who missed the match against Scotland through suspension, has been struggling with a back injury.
Italy: Andrea Marcato; Giulio Rubini, Gonzalo Canale, Mirco Bergamasco, Matteo Pratichetti; Luke McLean, Paul Griffen; Salvatore Perugini, Leonardo Ghiraldini, Carlos Nieto, Santiago Dellape, Marco Bortolami, Alessandro Zanni, Mauro Bergamasco, Sergio Parisse (capt).
Replacements: Franco Sbaraglini, Martin Castrogiovanni, Carlo Antonio Del Fava, Josh Sole, Pablo Canavosio, Luciano Orquera, Roberto Quartaroli.
WRU International Skills Coach Jason Strange is a busy man, combining the new role with that of Wales Under 20 attack coach, Ebbw Vale head coach and continuing to teach at Ebbw Fawr Learning Community.
Warren Gatland and Sam Warburton look ahead to this week's crunch RBS 6 Nations tie against France, where the Wales skipper in particular is keen to make his mark, as Paris has proved a bleak place for him in the past.
Following their historic win over England, Wales Under 20 suffered a narrow, 36-34 loss to their Scottish counterparts last weekend, despite outscoring them by five tries to three. Watch the match highlights and reaction.
WRU TV go behind the scenes with the Wales squad as they put the final touches in place ahead of the clash against Scotland at Murrayfield. Follow the squad on their captain's run, the kickers visit to Murrayfield and Neil Jenkins' press conference