Italy coach Nick Mallett has made two changes to his side after losing the first three matches in this season's RBS Six Nations.
Now his team face defending champions Wales in Saturday's RBS Six Nations game at Rome's Stadio Flaminio, desperate for a win, or even a try. Italy have not crossed the whitewash since a late score in Round 1 against a tiring England team who had already secured victory
But Mallett has not pressed panic button and shown faith with the majority of the side that lost 26-6 to Scotland in Edinburgh last time out.
to Leicester prop Martin Castrogiavanni is dropped to the bench, Gloucester's Carlos Nieto starting at tight-head.
Overmach Parma full-back Giulio Rubini, 21, is given a first start on the wing, Mirco Bergamasco moving back to centre with Gonzalo Garcia missing out. Uncapped Roberto Quartaroli is also brought onto the bench.
Rubini won his first cap as a replacement in last month's 26-6 defeat to Scotland, the Murrayfield loss having followed earlier reversals to England and Ireland.
Azzurri full-back Andrea Masi was last week ruled out of the Wales game because of injury. Masi, who missed the match against Scotland through suspension, has been struggling with a back injury.
Italy: Andrea Marcato; Giulio Rubini, Gonzalo Canale, Mirco Bergamasco, Matteo Pratichetti; Luke McLean, Paul Griffen; Salvatore Perugini, Leonardo Ghiraldini, Carlos Nieto, Santiago Dellape, Marco Bortolami, Alessandro Zanni, Mauro Bergamasco, Sergio Parisse (capt).
Replacements: Franco Sbaraglini, Martin Castrogiovanni, Carlo Antonio Del Fava, Josh Sole, Pablo Canavosio, Luciano Orquera, Roberto Quartaroli.
Sam Cross and Luke Treharne have been named as co-captains of the Wales Sevens side as head coach Gareth Williams names his 12-man squad to play in the first leg of the HSBC World Series in Dubai next weekend.
Bedwas head coach Steve Law and players Nicky Griffiths and Alun Rees extol the virtues of the close knit club as they prepare to host third place RGC 1404 - who are one place head of them on the Principality Premiership points table - on Saturday.
Many of the Wales squad have said Diolch (thank you) to someone who played an important part in their early playing days by nominating them to be invited to the Wales v South Africa match. One person, Gowerton Comprehensive geography teacher Mr Dean Mason was nominated by two of his former pupils, Dan Biggar and Sam Davies.
The second WRU disability rugby pilot has been delivered, this time in Caerphilly schools, culminating in a festival at the Caerphilly Centre of Sporting Excellence, Ystrad Mynach tomorrow. Plans are in place to set up a Disability Rugby Club in Newbridge to provide long-term playing opportunities.
WRU TV: Hear from inside the Wales camp as Neil Jenkins discusses this weekend's clash with South Africa and how the squad are looking to put in a strong performance to round of the 2016 Under Armour Series