Italy coach Nick Mallett has made two changes to his side after losing the first three matches in this season's RBS Six Nations.
Now his team face defending champions Wales in Saturday's RBS Six Nations game at Rome's Stadio Flaminio, desperate for a win, or even a try. Italy have not crossed the whitewash since a late score in Round 1 against a tiring England team who had already secured victory
But Mallett has not pressed panic button and shown faith with the majority of the side that lost 26-6 to Scotland in Edinburgh last time out.
to Leicester prop Martin Castrogiavanni is dropped to the bench, Gloucester's Carlos Nieto starting at tight-head.
Overmach Parma full-back Giulio Rubini, 21, is given a first start on the wing, Mirco Bergamasco moving back to centre with Gonzalo Garcia missing out. Uncapped Roberto Quartaroli is also brought onto the bench.
Rubini won his first cap as a replacement in last month's 26-6 defeat to Scotland, the Murrayfield loss having followed earlier reversals to England and Ireland.
Azzurri full-back Andrea Masi was last week ruled out of the Wales game because of injury. Masi, who missed the match against Scotland through suspension, has been struggling with a back injury.
Italy: Andrea Marcato; Giulio Rubini, Gonzalo Canale, Mirco Bergamasco, Matteo Pratichetti; Luke McLean, Paul Griffen; Salvatore Perugini, Leonardo Ghiraldini, Carlos Nieto, Santiago Dellape, Marco Bortolami, Alessandro Zanni, Mauro Bergamasco, Sergio Parisse (capt).
Replacements: Franco Sbaraglini, Martin Castrogiovanni, Carlo Antonio Del Fava, Josh Sole, Pablo Canavosio, Luciano Orquera, Roberto Quartaroli.
GB7s women left their England base to train in Wales this week. Olympic Games hopeful Rachael Burford gives WRU TV's Graeme Gillespie her thoughts on Welsh teammate Jasmine Joyce - a 'one touch wonder'
The GB7s women's squad is currently training at Wales' Centre of Excellence where assistant coach Richie Pugh tells WRU TV's Graeme Gillespie some 'tough calls' will have to be made when it comes to finalising the 12 spots for Rio's Olympic Games.
Wales U20's Billy McBryde is looking forward to starting his first game against New Zealand this afternoon in the World Rugby U20 Championship where his side are looking to gain revenge from last week's pool defeat to the Kiwis.