The Blue & Blacks include new signing Andy Williams in their 22-man squad for Saturday's Principality Premiership match against Llandovery at the Arms Park (2.30pm).
The international scrum-half completed his Premiership registration earlier this week and strengthens a Cardiff team that has won its last six cup and league fixtures - it's best winning sequence in four years.
Gareth Chapman adopts a new role as he starts at full-back with Shaun James, in his fiftieth game for the club, slotting into the outside centre position.
Gareth Davies, top scorer for the season with 131 points in all matches, continues at fly-half and the only change in the pack from the side that won at Narberth last weekend is the return of Rhys James at hooker.
Cardiff: Gareth Chapman; Ryan Howells, Shaun James, Darren Ryan, Chris Czekaj; Gareth Davies, Owen Ruttley (captain); Ian George, Rhys James, Kristian Gay, James Down, Damian Welch, Adam Powell, Craig Everett, Rhys Shellard.
Replacements: Kieran Crawford, Phil Osborne, Daniel Partridge, Jake Thomas, Andy Williams, Lee Jarvis, Roger Davies.
The last five years have been an emotional rollercoaster on and off the pitch for RGC1404. Promotion to the Principality Premiership was the culmination of five years of hard work and investment in North Wales. WRU TV caught up with prop Joe Simpson, who was one of the first intake of WRU North Wales Academy players in 2010.
Ebbw Vale captain Damien Hudd picked up the biggest accolade of the night at the 11th Principality Premiership Awards Evening held at Principality Stadium, after leading his side to the title for the first time.
Wales assistant coach Robin McBryde is predicting a tough battle against England on Sunday despite the fact they may not be considered to be at full strength. Players will be out to impress Eddie Jones which makes England a dangerous proposition, he says.
Wales U20 captain Tom Phillips and performance psychologist Dr Rich Neil explain why spending three days at Monmouth RFC has further strengthened the togetherness of the squad ahead of the #WorldRugbyU20s