Gavin Henson is one of three players who make an Ospreys return.
Gavin Henson, Adam Jones and Tommy Bowe return to the Ospreys for the mouthwatering Heineken Cup clash against Perpignan at the Stade Aime-Giral.
Sonny Parker suffered a fractured rib against Munster last weekend and is likely to be out of action for 4/6 weeks which has forced Ospreys coach Sean Holley into a re-shuffle.
The in-form Andrew Bishop moves out a place to outside centre to accommodate Henson's return while a groin injury to Jonathan Thomas means Filo Tiatia starts to form a formidable backrow alongside fellow Kiwi Marty Holah and skipper Ryan Jones who plays on the blindside flank.
Holley said: "Saturday's game is a huge fixture that will provide a real test of physical and mental strength, but it's an exciting challenge that we are all looking forward to.
"You can't fail to be excited about the prospect of challenging one of France's leading sides on their own patch, in front of a big crowd and in an electric atmosphere. Our players are the type who thrive on competing against the best in the world in front of big, passionate crowds and Perpignan certainly fit the bill.
"Our recent matches against the Blues and Munster were both hugely physical, and as such, have proved to be excellent preparation for this fixture. We welcome back six seasoned internationals into the starting 15, along with Jamie Nutbrown on the bench, whilst Tom Smith deservedly takes a place in the 22 after a fine performance last weekend.
"After reviewing the Munster match we have identified clear areas for improvement, and if we can hit the right performance marks in terms of what we've been working hard on this week then we will present a serious challenge to Perpignan."
Ospreys: L. Byrne; T. Bowe, A. Bishop, G. Henson, S. Williams; J. Hook, M. Phillips; P. James, R. Hibbard, A. Jones, I. Gough, A.W. Jones, R. Jones (capt), F. Tiatia, M. Holah. Reps: H. Bennett, C. Griffiths, L. Bateman, T. Smith, D. Biggar, J. Vaughton
Angus O'Brien has quickly settled into the Wales Sevens squad after solid performances in Hong Kong and Japan. With two rounds remaining in Glasgow and Twickenham on the World Series, WRU TV's Graeme Gillespie chats to the rising star.
Wales winger Luke Morgan has established himself as one of the deadliest finishers on the Sevens World Series. WRU TV's Graeme Gillespie catches up with him on the eve of this weekend's round in Glasgow.
All roads lead to Cardiff on Sunday for the SSE SWALEC Finals Day at the Millennium Stadium. Cambrian Welfare tackle Ystradgynlais in the Bowl final, Ystrad Rhondda play Newcastle Emlyn in the Plate final while defending champions Pontypridd face Bridgend in the Cup final.
WRU Chief Executive Roger Lewis, Deputy Minister for Culture, Sport and Tourism Ken Skates and WRU Chairman Gareth Davies earlier this week launched a new competition in conjunction with the WRU unveiling its archive room.
Welsh players and management joined Deputy Minister for Sport Ken Skates at the Pierhead Building, Cardiff Bay earlier this week to reveal the Union's pioneering school-club hub initiative has been so successful the project will now almost double the scale of the original project.
The Scarlets, Newport Gwent Dragons, Cardiff Blues and the Ospreys look ahead to Judgement Day III which sees the Blues take on the Ospreys (2.30) and the Dragons tackle the Scarlets (4.45pm) at the Millennium Stadium tomorrow afternoon.
Ystradgynlais and Ynysddu played out a titanic struggle at Taffs Well in the SSE SWALEC Bowl semi-final. At the end of the game neither team could be separated after a 15-15 stalemate but Ystradgynlais go through on try count.
Blues strike first in JD III battle - Newport Gwent Dragons lock Andrew Coombs, WRU referee Dylan Llyr Jones and Cardiff Blues hooker Matthew Rees decide dressing room allocations for Judgement Day III
Wales Under 18 captain Calum Haggett has received a conditional offer to read Biomedical Science at St Anne's College, Oxford. WRU chairman Gareth Davies went to meet Calum and Coleg y Cymoedd Principal Judith Evans to wish him luck in his exams and pass on some of his personal experience.