Gavin Henson is one of three players who make an Ospreys return.
Gavin Henson, Adam Jones and Tommy Bowe return to the Ospreys for the mouthwatering Heineken Cup clash against Perpignan at the Stade Aime-Giral.
Sonny Parker suffered a fractured rib against Munster last weekend and is likely to be out of action for 4/6 weeks which has forced Ospreys coach Sean Holley into a re-shuffle.
The in-form Andrew Bishop moves out a place to outside centre to accommodate Henson's return while a groin injury to Jonathan Thomas means Filo Tiatia starts to form a formidable backrow alongside fellow Kiwi Marty Holah and skipper Ryan Jones who plays on the blindside flank.
Holley said: "Saturday's game is a huge fixture that will provide a real test of physical and mental strength, but it's an exciting challenge that we are all looking forward to.
"You can't fail to be excited about the prospect of challenging one of France's leading sides on their own patch, in front of a big crowd and in an electric atmosphere. Our players are the type who thrive on competing against the best in the world in front of big, passionate crowds and Perpignan certainly fit the bill.
"Our recent matches against the Blues and Munster were both hugely physical, and as such, have proved to be excellent preparation for this fixture. We welcome back six seasoned internationals into the starting 15, along with Jamie Nutbrown on the bench, whilst Tom Smith deservedly takes a place in the 22 after a fine performance last weekend.
"After reviewing the Munster match we have identified clear areas for improvement, and if we can hit the right performance marks in terms of what we've been working hard on this week then we will present a serious challenge to Perpignan."
Ospreys: L. Byrne; T. Bowe, A. Bishop, G. Henson, S. Williams; J. Hook, M. Phillips; P. James, R. Hibbard, A. Jones, I. Gough, A.W. Jones, R. Jones (capt), F. Tiatia, M. Holah. Reps: H. Bennett, C. Griffiths, L. Bateman, T. Smith, D. Biggar, J. Vaughton
Despite drawing with Ireland in the opening round of the RBS 6 Nations, Wales defence coach Shaun Edwards believes the championship 'is still in our hands' as he prepares his side to face Scotland at Principality Stadium tomorrow.
Meet the members of the WRU's inaugural Youth Board - after an online selection process which saw a host of high calibre candidates submit video applications the WRU has made its first 15 appointments.The board is made up of individuals aged between 16 and 21, and will meet for the first time at Principality Stadium on Monday 15th February.
The Wales Women's team headed to Dare Valley Country Park on a team bonding exercise as the entire squad got together for the very first time in preparation for this season's Six Nations championship which kicks off on Saturday with a clash against defending champions Ireland, in Donnybrook.