Gavin Henson is one of three players who make an Ospreys return.
Gavin Henson, Adam Jones and Tommy Bowe return to the Ospreys for the mouthwatering Heineken Cup clash against Perpignan at the Stade Aime-Giral.
Sonny Parker suffered a fractured rib against Munster last weekend and is likely to be out of action for 4/6 weeks which has forced Ospreys coach Sean Holley into a re-shuffle.
The in-form Andrew Bishop moves out a place to outside centre to accommodate Henson's return while a groin injury to Jonathan Thomas means Filo Tiatia starts to form a formidable backrow alongside fellow Kiwi Marty Holah and skipper Ryan Jones who plays on the blindside flank.
Holley said: "Saturday's game is a huge fixture that will provide a real test of physical and mental strength, but it's an exciting challenge that we are all looking forward to.
"You can't fail to be excited about the prospect of challenging one of France's leading sides on their own patch, in front of a big crowd and in an electric atmosphere. Our players are the type who thrive on competing against the best in the world in front of big, passionate crowds and Perpignan certainly fit the bill.
"Our recent matches against the Blues and Munster were both hugely physical, and as such, have proved to be excellent preparation for this fixture. We welcome back six seasoned internationals into the starting 15, along with Jamie Nutbrown on the bench, whilst Tom Smith deservedly takes a place in the 22 after a fine performance last weekend.
"After reviewing the Munster match we have identified clear areas for improvement, and if we can hit the right performance marks in terms of what we've been working hard on this week then we will present a serious challenge to Perpignan."
Ospreys: L. Byrne; T. Bowe, A. Bishop, G. Henson, S. Williams; J. Hook, M. Phillips; P. James, R. Hibbard, A. Jones, I. Gough, A.W. Jones, R. Jones (capt), F. Tiatia, M. Holah. Reps: H. Bennett, C. Griffiths, L. Bateman, T. Smith, D. Biggar, J. Vaughton
Twelve young people have been selected to follow a one year WRU Coach Core apprenticeship programme. Coach Core was set up by the Royal Foundation of the Duke and Duchess of Cambridge and Prince Harry as part of the Olympics legacy in 2012 and the Duke of Cambridge was on hand to meet the apprentices on their first day in the job. The programme has been funded by the Hunter Foundation.
The WRU has launched a campaign to create a long term legacy for Welsh club rugby by highlighting the advantages of volunteering. Rhian Edwards, a volunteer at Seven Sisters, has enjoyed many benefits of her volunteering at a grassroots rugby club including being part of the Rugby World Cup volunteer workforce after being nominated by the WRU - and the WRU is asking for more people to develop their 'Welsh rugby roots'.
Wales head coach Warren Gatland and captain Sam Warburton say their first prioirty on Sunday in the opening game of the World Cup is to win against Uruguay and not get overly concerned with points difference.
With only days to go until the biggest rugby competition in the world begins, rugby fans visiting Cardiff this autumn will be able to enjoy a special display at National Museum Cardiff as part of the celebrations surrounding the Rugby World Cup.