With Richard Hodges away on Wales 7's duty Chris Ower takes charge and makes seven changes to the Wanderers line-up on their return to league action at Cross Keys.
Jason Pocock and Steve Cullen return in the back three and James Thomas gets a start at centre.
In the pack Rhys Gill and Nathan Trevett step into the front row with Ben Rose and Mike Grimes returning in the back-row. Nick Kelly regains the captaincy from Scott Andrews.
Glamorgan Wanderers: 15. Jason Pocock 14. Steve Cullen 13. Jamie Jones 12. James Thomas 11. Robin Lock 10. Scott Sneddon 9. Glenn Holloway; 1. Rhys Gill 2. Ross Johnson 3. Nathan Trevett 4. Gareth Knight 5. Nick Kelly (capt) 6. Nio Aiono 7. Ben Rose 8. Mike Grimes.
Replacements: 16. Ryan Price 17. Mark O'Leary 18. Tom Evans 19. Richard Thomas 20. Ben White 21. Luke Evans 22. Gareth Morris
As the countdown continues for RWC2015, Tournament Chief Executive Debbie Jevans visited the Millennium Stadium to discuss preparations for the eight matches and reveal the positive news that 100,000 tickets for games at the home of Welsh rugby have sold in the last seven days.
Jason Harries is targeting a first win on the World Series circuit this season with Wales. The series returns to action this weekend in Dubai where Harries is part of a team hoping to build from its efforts in round one in October.
Wales skipper Jevon Groves says his side have addressed a few points from Gold Coast and aim to 'hit the ground running' in the next two rounds of the World Series, kicking off with this weekend in Dubai before heading off to South Africa next week.
Wales Sevens manager Steff Thomas is hopeful his side can build from a quarter-final spot in the opening round of the World Series in Australia when his side take part in the forthcoming double header in Dubai and South Africa.