Llanelli make six changes, and two positional to the side which lost 19-16 to Aberavon last weekend for the clash against Bedford.
Hooker and influential captain Craig Hawkins again misses out due to injury and young Wales Under 20 hooker Rhys Lawrence gets the nod. He will be propped up by brothers Shaun and Aled Hopkins.
No 8 Rob McCusker will captain the team and along with energetic flankers Nic Cudd and Johnathan Edwards will form a formidable backrow.
Young Johnny Lewis in only his third game for the club makes his bow in the competition.
Llanelli 15 Jonny Lewis 14 Nick Reynolds 13 Steve Martin 12 Scott Williams 11 Andy Fenby 10 Dan Newton 9 Tavis Knoyle; 1 Shaun Hopkins 2 Rhys Lawrence 3 Aled Hopkins 4 Adam Powell 5 Aaron Shingler 6 Johnny Edwards 7 Nic Cudd 8 Rob McCusker (capt)
Replacements 16 Ian Jones 17 Luke Lewis 18 Jamie Corsi 19 Nathan White 20 Duane Eager 21 Gareth Davies 22 Steve Shingler
As the countdown continues for RWC2015, Tournament Chief Executive Debbie Jevans visited the Millennium Stadium to discuss preparations for the eight matches and reveal the positive news that 100,000 tickets for games at the home of Welsh rugby have sold in the last seven days.
Jason Harries is targeting a first win on the World Series circuit this season with Wales. The series returns to action this weekend in Dubai where Harries is part of a team hoping to build from its efforts in round one in October.
Wales skipper Jevon Groves says his side have addressed a few points from Gold Coast and aim to 'hit the ground running' in the next two rounds of the World Series, kicking off with this weekend in Dubai before heading off to South Africa next week.
Wales Sevens manager Steff Thomas is hopeful his side can build from a quarter-final spot in the opening round of the World Series in Australia when his side take part in the forthcoming double header in Dubai and South Africa.