Llanelli make six changes, and two positional to the side which lost 19-16 to Aberavon last weekend for the clash against Bedford.
Hooker and influential captain Craig Hawkins again misses out due to injury and young Wales Under 20 hooker Rhys Lawrence gets the nod. He will be propped up by brothers Shaun and Aled Hopkins.
No 8 Rob McCusker will captain the team and along with energetic flankers Nic Cudd and Johnathan Edwards will form a formidable backrow.
Young Johnny Lewis in only his third game for the club makes his bow in the competition.
Llanelli 15 Jonny Lewis 14 Nick Reynolds 13 Steve Martin 12 Scott Williams 11 Andy Fenby 10 Dan Newton 9 Tavis Knoyle; 1 Shaun Hopkins 2 Rhys Lawrence 3 Aled Hopkins 4 Adam Powell 5 Aaron Shingler 6 Johnny Edwards 7 Nic Cudd 8 Rob McCusker (capt)
Replacements 16 Ian Jones 17 Luke Lewis 18 Jamie Corsi 19 Nathan White 20 Duane Eager 21 Gareth Davies 22 Steve Shingler
The last five years have been an emotional rollercoaster on and off the pitch for RGC1404. Promotion to the Principality Premiership was the culmination of five years of hard work and investment in North Wales. WRU TV caught up with prop Joe Simpson, who was one of the first intake of WRU North Wales Academy players in 2010.
Ebbw Vale captain Damien Hudd picked up the biggest accolade of the night at the 11th Principality Premiership Awards Evening held at Principality Stadium, after leading his side to the title for the first time.
Wales assistant coach Robin McBryde is predicting a tough battle against England on Sunday despite the fact they may not be considered to be at full strength. Players will be out to impress Eddie Jones which makes England a dangerous proposition, he says.
Wales U20 captain Tom Phillips and performance psychologist Dr Rich Neil explain why spending three days at Monmouth RFC has further strengthened the togetherness of the squad ahead of the #WorldRugbyU20s