Llanelli make six changes, and two positional to the side which lost 19-16 to Aberavon last weekend for the clash against Bedford.
Hooker and influential captain Craig Hawkins again misses out due to injury and young Wales Under 20 hooker Rhys Lawrence gets the nod. He will be propped up by brothers Shaun and Aled Hopkins.
No 8 Rob McCusker will captain the team and along with energetic flankers Nic Cudd and Johnathan Edwards will form a formidable backrow.
Young Johnny Lewis in only his third game for the club makes his bow in the competition.
Llanelli 15 Jonny Lewis 14 Nick Reynolds 13 Steve Martin 12 Scott Williams 11 Andy Fenby 10 Dan Newton 9 Tavis Knoyle; 1 Shaun Hopkins 2 Rhys Lawrence 3 Aled Hopkins 4 Adam Powell 5 Aaron Shingler 6 Johnny Edwards 7 Nic Cudd 8 Rob McCusker (capt)
Replacements 16 Ian Jones 17 Luke Lewis 18 Jamie Corsi 19 Nathan White 20 Duane Eager 21 Gareth Davies 22 Steve Shingler
Meet the members of the WRU's inaugural Youth Board - after an online selection process which saw a host of high calibre candidates submit video applications the WRU has made its first 15 appointments.The board is made up of individuals aged between 16 and 21, and will meet for the first time at Principality Stadium on Monday 15th February.
The Wales Women's team headed to Dare Valley Country Park on a team bonding exercise as the entire squad got together for the very first time in preparation for this season's Six Nations championship which kicks off on Saturday with a clash against defending champions Ireland, in Donnybrook.
Wales Head Coach Warren Gatland discusses his team selection for the opening round of the RBS 6 Nations where he leads his side against Ireland, on Sunday. As WRU TV's Luke Brodley discovers, Gatland is fully aware of the challenges the defending champions pose
WRUTV caught up with Wales Women captain Rachel Taylor at the RBS 6 Nations launch and how a good crowd really helps boost the girls performance. Tickets for all three Women's home games at The Gnoll, Neath are available from www.wru.wales/tickets