Llanelli make six changes, and two positional to the side which lost 19-16 to Aberavon last weekend for the clash against Bedford.
Hooker and influential captain Craig Hawkins again misses out due to injury and young Wales Under 20 hooker Rhys Lawrence gets the nod. He will be propped up by brothers Shaun and Aled Hopkins.
No 8 Rob McCusker will captain the team and along with energetic flankers Nic Cudd and Johnathan Edwards will form a formidable backrow.
Young Johnny Lewis in only his third game for the club makes his bow in the competition.
Llanelli 15 Jonny Lewis 14 Nick Reynolds 13 Steve Martin 12 Scott Williams 11 Andy Fenby 10 Dan Newton 9 Tavis Knoyle; 1 Shaun Hopkins 2 Rhys Lawrence 3 Aled Hopkins 4 Adam Powell 5 Aaron Shingler 6 Johnny Edwards 7 Nic Cudd 8 Rob McCusker (capt)
Replacements 16 Ian Jones 17 Luke Lewis 18 Jamie Corsi 19 Nathan White 20 Duane Eager 21 Gareth Davies 22 Steve Shingler
Twelve young people have been selected to follow a one year WRU Coach Core apprenticeship programme. Coach Core was set up by the Royal Foundation of the Duke and Duchess of Cambridge and Prince Harry as part of the Olympics legacy in 2012 and the Duke of Cambridge was on hand to meet the apprentices on their first day in the job. The programme has been funded by the Hunter Foundation.
The WRU has launched a campaign to create a long term legacy for Welsh club rugby by highlighting the advantages of volunteering. Rhian Edwards, a volunteer at Seven Sisters, has enjoyed many benefits of her volunteering at a grassroots rugby club including being part of the Rugby World Cup volunteer workforce after being nominated by the WRU - and the WRU is asking for more people to develop their 'Welsh rugby roots'.
Wales head coach Warren Gatland and captain Sam Warburton say their first prioirty on Sunday in the opening game of the World Cup is to win against Uruguay and not get overly concerned with points difference.
With only days to go until the biggest rugby competition in the world begins, rugby fans visiting Cardiff this autumn will be able to enjoy a special display at National Museum Cardiff as part of the celebrations surrounding the Rugby World Cup.