James Goode makes his Ospreys debut after arriving on trial last week while James King and Justin Tipuric make their first starts for the region after debuting over the last two weeks.
Will Taylor and Hanno Dirksen will make their Ospreys debuts if they come off the bench during the game. Ross Davies made his Ospreys debut as a replacement last weekend, and along with Richard Kelly and Matthew Jarvis has just one Ospreys appearance to date.
Rhys Webb returns to action ahead of schedule following ACL and shoulder reconstructions at the end of April
Ospreys Coach Jonathan Humphreys commented: "We're looking forward to playing Bath on Saturday, and what will be another chance to test ourselves against Guinness Premiership opposition. I've got no doubts that Bath will be looking at our current situation here, with injuries and unavailability and will be targeting a win, but we'll travel full of self belief and confidence in the players that we put out. It's a fantastic opportunity for some of these guys to put their hand up and show what they can do, and while it's been tough preparing for the game, I have to say that the attitude and application of the squad has been first class.
"Bath haven't had the best of runs recently, if you just look the W's or L's in the column, but that doesn't tell the full story. They've put on some good performances and recorded some really narrow defeats as well as a draw against Leicester, so we now that they will pose a real threat. Bath sides have always had a strong pack, and that is what they are trying to build there. It's going to be a real test for our young side, and one that I'd like to think that they would enjoy and learn from as they continue their development.
"With the new format of the LV= Cup, there is an extra game in the pool stages this year, so with us both losing last weekend, we have an opportunity to bounce back and keep alive our hopes of progressing."
Following a convincing display against Saracens last Sunday, Bath Head Coach Steve Meehan will be looking for yet another strong performance from the team, especially the younger players who will be challenging for future match time.
"We went out against a very good Saracens side," admitted Meehan. "And we chose to give some players that were coming back from injury, and some of our younger players who have been training very well, the opportunity to play.
"If you took the score line out of it we probably got a lot more out of the game than Saracens did with regards to knowing a bit more about some of our players and where we are as a squad. I am pretty happy with that."
Due to a shoulder injury to Rhys Crane, Academy winger Nick Scott gets a place on the bench and with David Barnes having sustained an injury during England training, he is replaced on the bench by David Flatman.
Luke Watson makes his debut for Bath and whilst he is on the bench Meehan is sure to give him a good run out against the welsh side.
"What we want to do is improve on the things we have been working on in training and give particularly our young players a good run out, this time in front of their home supporters, and I hope they deliver the same sort of performance as they did last week."
Ospreys 15 Barry Davies 14 Nicky Thomas 13 Sonny Parker 12 Andrew Bishop 11 Ashley Beck 10 Gareth Owen 9 Liam Davies; 1 Ryan Bevington 2 Ed Shervington 3 Cai Griffiths 4 James King 5 James Goode 6 Jerry Collins (Capt) 7 Justin Tipuric 8 Tom Smith
Replacements16 Richard Hibbard 17 Will Taylor 18 Ross Davies 19 Richard Kelly 20 Steve Tandy 21 Rhys Webb 22 Matthew Jarvis 23 Hanno Dirksen
Bath Rugby 15. Jack Cuthbert 14. Joe Maddock 13. Tom Cheeseman 12. Ben Williams 11. Michael Stephenson 10. Ryan Davis 9. Mike Baxter: 1. Nathan Catt 2. Rob Hawkins 3. Aaron Jarvis 4. Scott Hobson 5. Peter Short (capt) 6. Andy Beattie 7. Guy Mercer 8. Ben Skirving
Replacements: 16. Lee Mears 17. David Flatman 18. Mark Lilley 19. Daniel Browne 20. Luke Watson 21. Chris Cook 22. Paul Roberts 23. Nick Scott
Wales U20 duo Leon Brown and Lloyd Lewis face a busy couple of weeks ahead. Not only will they have a Junior World Championship to take part in, they are both sitting A Level exams during the competition.
Wales U20 face a tough group in the Junior World Championship with France, England and Japan lying in wait but Attack coach Jason Strange and back rower Tom Phillips are looking forward to the campaign ahead.
Angus O'Brien has quickly settled into the Wales Sevens squad after solid performances in Hong Kong and Japan. With two rounds remaining in Glasgow and Twickenham on the World Series, WRU TV's Graeme Gillespie chats to the rising star.
Wales winger Luke Morgan has established himself as one of the deadliest finishers on the Sevens World Series. WRU TV's Graeme Gillespie catches up with him on the eve of this weekend's round in Glasgow.
All roads lead to Cardiff on Sunday for the SSE SWALEC Finals Day at the Millennium Stadium. Cambrian Welfare tackle Ystradgynlais in the Bowl final, Ystrad Rhondda play Newcastle Emlyn in the Plate final while defending champions Pontypridd face Bridgend in the Cup final.
WRU Chief Executive Roger Lewis, Deputy Minister for Culture, Sport and Tourism Ken Skates and WRU Chairman Gareth Davies earlier this week launched a new competition in conjunction with the WRU unveiling its archive room.
Welsh players and management joined Deputy Minister for Sport Ken Skates at the Pierhead Building, Cardiff Bay earlier this week to reveal the Union's pioneering school-club hub initiative has been so successful the project will now almost double the scale of the original project.
The Scarlets, Newport Gwent Dragons, Cardiff Blues and the Ospreys look ahead to Judgement Day III which sees the Blues take on the Ospreys (2.30) and the Dragons tackle the Scarlets (4.45pm) at the Millennium Stadium tomorrow afternoon.
Ystradgynlais and Ynysddu played out a titanic struggle at Taffs Well in the SSE SWALEC Bowl semi-final. At the end of the game neither team could be separated after a 15-15 stalemate but Ystradgynlais go through on try count.