Both sides will be without their international contingent with Danny Care and Ugo Monye in Martin Johnson's starting line-up for tomorrow's game against Australia. Chris Robshaw will lead out a similarly strong Quins team to the one that started last Saturday against London Irish.
The only change to the starting line-up is in the front row where Aston Croall, Chris Brooker and James Johnston join the Quins pack. John Andress moves to the bench.
The remaining changes are on the bench, where new signing Matt Cairns makes his debut, joining fellow team mate Waisea Luvenyali, who makes his first appearance for Quins this season.
Harlequins: 1. Aston Croall 2. Chris Brooker 3. James Johnston 4. James Percival 5. George Robson 6. Chris Robshaw (capt) 7. Neil McMillan 8. Tom Guest 9. Steve So'oialo 10. Rory Clegg 11. Josh Drauniniu 12. Nils Mordt 13. Gonzalo Tiesi 14. David Strettle 15. Mike Brown
Replacements: 16. Matt Cairns 17. Mark Lambert 18. John Andress 19. Lewis Stevenson 20. Chris York 21. Karl Dickson 22. Waisea Luvenyali 23. George Lowe