Ryan Jones has withdrawn from the Wales side to take on Australia in the Invesco Perpetual Series climax at the Millennium Stadium on Saturday (Kick-off 5.30pm).
Gethin Jenkins will captain the team and Jones is replaced at No8 by Andy Powell, who moves across the back row, with Dragons flanker Dan Lydiate promoted from the bench to the blindside to win his second cap.
Lydiate's place as a replacement is taken up by Sam Warburton, who faces the prospect of tackling the Wallabies for the second time in a week after representing the Cardiff Blues against their midweek touring side on Tuesday.
"Ryan pulled up in Tuesday's conditioning session with a back problem," said Wales physio Mark Davies.
"This obviously needed time to settle and unfortunately the problem has not resolved in time for him to be available on Saturday.
"He has been receiving treatment and was unable to train yesterday, but today we have taken the decision that he is simply not going to be ready to take the field."
Sam WARBURTON (CARDIFF BLUES - Cap No 1,070)
DoB: 05.10.88. 1.88m / 6'2". 15st 9lbs / 99kgs
International record: 2 caps (W 2)
Principality Stadium will host the UEFA Champions League Final in six weeks' time. WRU chairman Gareth Davies, Football Association of Wales chief executive Jonathan Ford and Ambassador Ian Rush joined young sports fans at the trophy arrival at the venue to celebrate the magnitude of the event on Saturday 3rd June (kick-off 19.45).
British and Irish Lions captain Sam Warburton is looking forward to bringing together players from Ireland, Scotland, England and Wales for the biggest challenge of their careers - a series against world champions, New Zealand.
For the fifth year running, Wales referee Nigel Owens will be in charge of proceedings at Judgement Day V at Principality Stadium. It promises to be 'extra special' for the Wales' favourite ref, as he will be making his 150th appearance in the league.
There will be no shortage of inside knowledge from Bowl Finalists Caerphilly and Amman United when they face each other on Sunday at National Finals Day. Caerphilly hooker Rhys Cleverly knows the Principality Stadium pitch better than most as a matchday groundsman, while Amman United can look to Wales' record try scorer Shane Williams for some helpful advice.
Two hundred and 40 teams competed in the inaugural Urdd WRU 7s held at Pencoed last week with Welsh internationals Steff Andrews and Jasmine Joyce impressed with the talent on display, as was Urdd chief executive, Sioned Hughes.
The countdown is on for Judgement Day V as tickets for the big day at Principality Stadium soar through the 50,000 mark. Players and coaches alike are bursting at the seams to play in the double header with Dragons coach Kingsley Jones claiming there is a 'real buzz' about the event.
WRU TV went behind the scenes when the four regions got together to test their skill set for the BBC's Scrum V Live rugby show, at the WRU National Centre of Excellene in the build up to Judgement Day V. Blues' Matthew Morgan was one of the stars of the show while the Dragons' Cory Hill proved a surprise package...the full set of results will be revealed on tv screens on matchday
Wales assistant coach Richie Pugh is confident his side can cause a few headaches in the Hong Kong Sevens this weekend. In a tough group, Wales kick off their campaign against New Zealand on Friday before playing Japan and Fiji, who are chasing their third consecutive Hong Kong title, on Saturday.
Bedwas had to overcome a stubborn Carmarthen Quins side before winning the Foster's Challenge Cup final in Bridgend with a 23-18 victory. Bedwas captain Nicky Griffiths pays tribute to his side who have claimed the club's first piece of silverware in the modern era.
Team coach Brett Davey is aiming to keep his unbeaten run in cup finals at Principality Stadium intact when his side take on Amman United in the WRU Bowl final, after he guided Caerphilly to a 20-14 win against Cilfynydd in the semi-finals.
Penallta are hoping to go one step further than last season when falling to Bedlinog in the WRU Plate Final. After a titanic struggle against Nant Conwy, they have given themselves a great chance, after a hard fought 18-13 semi-final victory.