Assistant coach Sean Holley has warned the USA Eagles to expect a clinical performance from Wales in the Chicago encounter.
He has urged his team to be more ruthless in attack and defence than they were in their 32 points to 23 victory over Canada a week ago.
He said:"We want to put on a show for the people back home and the people who have travelled out here to see us play.
"We are looking for a good performance to round off the tour and the season. We are expecting a much more clinical performance this week and we need to be a lot more ruthless in attack and defence."
The Wales defence coach warned against complacency saying home advantage will help the USA Eagles mount their offensive.
He explained:"We are really looking to focus on ourselves in the light of the improvements we know are needed from last weeks performance.
"The Chicago pitch is a lot wider which offers more open space and that suits our style of play. The boys were impressed with the stadium and now they just can't wait to get out there and play rugby."
He also spoke of the valuable lessons he has learnt from his first experience within the Wales national coaching team. "I have learnt a lot and a lot of what goes on here is about attention to detail," he said. "If you get the detail right you reap the rewards, but if you get it wrong you face the consequences."
The Wales caretaker defence coach said he valued the opportunity the tour had given him to concentrate on one facet of play. He concluded "I have definitely learnt things which will help me when I go back to the Ospreys after this,"
Wales Head Coach Rob Howley talks to WRU TV's Sebastian Barrett about the 36-man squad he has just named for the forthcoming Under Armour series, which includes two uncapped players, Ospreys duo Sam Davies and Rory Thornton.
Head coach Rowland Phillips is deligthed he can now call BT Sport Cardiff Arms Park home for his Wales Women's side, who launch their international season next month with games against Scotland and UK Armed Forces in the heart of the capital city.
Wales Sevens star Sam Cross has put his home town club of Brynmawr on the map after winning a silver medal at the Rio Olympics with Team GB. His club have now honoured him by naming their players bar after him, as WRU TV discovered at the official launch, recently.
One of the newest members of the Principality Premiership, Bargoed admit it's proving to be a steep learning curve at the highest level, but are determined to become a force to be reckoned with. WRU TV visited the club last weekend when they took on Llanelli.
Table-topping Aberavon travel to north Wales to tackle RGC 1404 as both teams defend unbeaten starts to the season in the Principality Premiership. WRU TV's Graeme Gillespie visited the Wizards to see how their preparations were going for the game of the weekend.
The Half a Game initiative is currently sweeping across Wales and proving a major success. The scheme aims to give every young player at least half a game every weekend. WRU TV recently visited a festival in Narberth where clubs have fully embraced the initiative.
Both Bargoed and Swansea were seeking their first win of the Principality Premiership season this afternoon. It proved a fruitful day for the hosts - not only did they win, but Bargoed claimed a try bonus point.
Cardiff managed to keep their unbeaten record at home intact, but only just as Bridgend made them work extremely hard before the Blue and Blacks secured a hard fought Principality Premiership win at the BT Sport Arms Park last night.
Former Wales back row Andy Powell gives a guided tour of The Wern, home of Merthyr RFC, who are determined to prove a lot of people wrong and make their mark in their first season in the Principality Premiership.