Assistant coach Sean Holley has warned the USA Eagles to expect a clinical performance from Wales in the Chicago encounter.
He has urged his team to be more ruthless in attack and defence than they were in their 32 points to 23 victory over Canada a week ago.
He said:"We want to put on a show for the people back home and the people who have travelled out here to see us play.
"We are looking for a good performance to round off the tour and the season. We are expecting a much more clinical performance this week and we need to be a lot more ruthless in attack and defence."
The Wales defence coach warned against complacency saying home advantage will help the USA Eagles mount their offensive.
He explained:"We are really looking to focus on ourselves in the light of the improvements we know are needed from last weeks performance.
"The Chicago pitch is a lot wider which offers more open space and that suits our style of play. The boys were impressed with the stadium and now they just can't wait to get out there and play rugby."
He also spoke of the valuable lessons he has learnt from his first experience within the Wales national coaching team. "I have learnt a lot and a lot of what goes on here is about attention to detail," he said. "If you get the detail right you reap the rewards, but if you get it wrong you face the consequences."
The Wales caretaker defence coach said he valued the opportunity the tour had given him to concentrate on one facet of play. He concluded "I have definitely learnt things which will help me when I go back to the Ospreys after this,"
After two years in the international wilderness, Adi Taviner is hoping to make up for lost time when she takes part in her second Women's Rugby World Cup which kicks off in Paris next Friday where Wales take on hosts, France.
The WRU's Women and Girls legacy events - #TRY OUR GAME have proved popular this week with current players and newcomers to the game learning new skills and picking up tips from national squad players.
We caught up with Shona and Ellie from the Wales women team ahead of the start of the Women's Rugby World Cup in Paris next month at a recent women's training session to encourage and promote more women and girls to try their hand at rugby. #tryourgame
The Women's Rugby World Cup warm-up clash between Wales and USA proved bittersweet for centre Elen Evans. Despite being one of the star performers on the day on her 50th Test appearance, USA edged home 10-7 at Cross Keys.
Wales completed their Junior World Championship campaign with a victory over Samoa. Team manager Mark Taylor and No 8 James Benjamin reflect on a tournament which saw Wales win three games and lose two.