Assistant coach Sean Holley has warned the USA Eagles to expect a clinical performance from Wales in the Chicago encounter.
He has urged his team to be more ruthless in attack and defence than they were in their 32 points to 23 victory over Canada a week ago.
He said:"We want to put on a show for the people back home and the people who have travelled out here to see us play.
"We are looking for a good performance to round off the tour and the season. We are expecting a much more clinical performance this week and we need to be a lot more ruthless in attack and defence."
The Wales defence coach warned against complacency saying home advantage will help the USA Eagles mount their offensive.
He explained:"We are really looking to focus on ourselves in the light of the improvements we know are needed from last weeks performance.
"The Chicago pitch is a lot wider which offers more open space and that suits our style of play. The boys were impressed with the stadium and now they just can't wait to get out there and play rugby."
He also spoke of the valuable lessons he has learnt from his first experience within the Wales national coaching team. "I have learnt a lot and a lot of what goes on here is about attention to detail," he said. "If you get the detail right you reap the rewards, but if you get it wrong you face the consequences."
The Wales caretaker defence coach said he valued the opportunity the tour had given him to concentrate on one facet of play. He concluded "I have definitely learnt things which will help me when I go back to the Ospreys after this,"
As the countdown continues for RWC2015, Tournament Chief Executive Debbie Jevans visited the Millennium Stadium to discuss preparations for the eight matches and reveal the positive news that 100,000 tickets for games at the home of Welsh rugby have sold in the last seven days.
Jason Harries is targeting a first win on the World Series circuit this season with Wales. The series returns to action this weekend in Dubai where Harries is part of a team hoping to build from its efforts in round one in October.
Wales skipper Jevon Groves says his side have addressed a few points from Gold Coast and aim to 'hit the ground running' in the next two rounds of the World Series, kicking off with this weekend in Dubai before heading off to South Africa next week.
Wales Sevens manager Steff Thomas is hopeful his side can build from a quarter-final spot in the opening round of the World Series in Australia when his side take part in the forthcoming double header in Dubai and South Africa.