Ospreys and Wales prop Adam Jones and Ireland centre Brian O'Drisoll, who both suffered injuries against South Africa in Saturday's titanic second Test in Pretoria, will return to Britain tomorrow.
O'Driscoll and Jones were among several Lions players who had to leave the field with injuries in a match where the world champions claimed the series with one Test still to play.
Jones dislocated his right shoulder during the match and received hospital treatment in order to have the shoulder put back into place. He will return home for further specialist opinion and treatment.
Jones said, "It is always disappointing to be ruled out of a Test series through injury but I am proud of what the squad and I have achieved on the tour. Personally I will always remember playing in the two first Tests and especially running on for my debut in the starting XV at Loftus Versfeld. My heart will be with the boys on Saturday."
O'Driscoll suffered a concussion in the match and began the return to play on Monday. However it soon became clear at the start of the process that he was not going to be ready for a return to action for Saturday's third Test in Johannesburg.
O'Driscoll said, "Being a part of the 2009 British & Irish Lions squad has been one of the highlights of my career. We were unbeaten leading into the Test matches and it is a shame that the results in the Tests did not go our way but sport comes down to fine margins at times. We could easily have won the first two Tests but it wasn't to be.
"I have decided to return home to my family this week after a very long season and to ensure I give myself every opportunity to recouperate."
Gethin Jenkins who suffered a broken cheekbone in the same match and was also ruled out of the rest of the tour will stay with the tour party. He has a review appointment with the surgeon on Friday. With just one match remaining on the tour the British & Irish Lions will not call for replacement players.
James Robson provided further medical update "The two other players who suffered injury in the second test, Tommy Bowe and Jamie Roberts, continue to be assessed on a daily basis but at this point they are making encouraging progress."
When the Wales squad were asked to nominate individuals who played a big part in their early playing days, Wales and Dragons full back and wing Hallam Amos thought of his former Monmouth School rugby coach John Bevan.
Sam Cross and Luke Treharne have been named as co-captains of the Wales Sevens side as head coach Gareth Williams names his 12-man squad to play in the first leg of the HSBC World Series in Dubai next weekend.
Bedwas head coach Steve Law and players Nicky Griffiths and Alun Rees extol the virtues of the close knit club as they prepare to host third place RGC 1404 - who are one place head of them on the Principality Premiership points table - on Saturday.
Many of the Wales squad have said Diolch (thank you) to someone who played an important part in their early playing days by nominating them to be invited to the Wales v South Africa match. One person, Gowerton Comprehensive geography teacher Mr Dean Mason was nominated by two of his former pupils, Dan Biggar and Sam Davies.
The second WRU disability rugby pilot has been delivered, this time in Caerphilly schools, culminating in a festival at the Caerphilly Centre of Sporting Excellence, Ystrad Mynach tomorrow. Plans are in place to set up a Disability Rugby Club in Newbridge to provide long-term playing opportunities.
WRU TV: Hear from inside the Wales camp as Neil Jenkins discusses this weekend's clash with South Africa and how the squad are looking to put in a strong performance to round of the 2016 Under Armour Series