Both teams enter this afternoon's clash with two wins apiece in the championship.
Wales are hoping to make this afternoon an uncomfortable day at the office for Ireland as the men in green attempt to keep their RBS 6 Nations title ambitions on track (KO 5pm).
Irish players have tasted a lot of success in Cardiff and don't arrive with the baggage of a lot of other sides who fear the Millennium Stadium factor.
Ireland clinched the Grand Slam in 2009 at the Millennium Stadium while the Munster players within the Irish squad have tasted double success in the Heineken Cup with victories in 2006 and 2008.
Wales forwards coach Robin McBryde is fully aware Matthew Rees and co have it all to do if they are to keep their own title ambitions alive. But with both teams having a similar record with two wins from three games, something will have to give this afternoon.
McBryde said: "I think it's fair to say both teams are struggling to find their top form, to really play at the best of their ability and have that accuracy under the pressure that international rugby brings.
"Hopefully, both teams will bring their best game to the table. We know how comfortable Ireland are coming to Cardiff, so hopefully we can make it as uncomfortable as possible. It will be about the small margins."
Meaanwhile Ireland fly-half Ronan O'Gara needs just two points to reach 1,000 at international level which would put him alongside just four other players - Neil Jenkins, Jonny Wilkinson, Dan Carter and Diego Dominguez.
Jenkins said: "What can you say about Ronan? He has done everything. He is a Munster legend, and now he needs just a couple of points for a 1,000.
"If I see him I am sure I will have a bit of banter with him, as he is getting close to my number (of points). He is a legend of the game and a legend of Irish rugby."
Wales: L Byrne (Ospreys); L Halfpenny (Cardiff Blues), J Roberts (Cardiff Blues), J Davies (Scarlets), S Williams (Ospreys); J Hook (Ospreys), M Phillips (Ospreys); P James (Ospreys), M Rees (Scarlets, capt), C Mitchell (Ospreys), B Davies (Cardiff Blues), A-W Jones (Ospreys), D Lydiate (Newport Gwent Dragons), S Warburton (Cardiff Blues), R Jones (Ospreys).
Replacements: R Hibbard (Ospreys), J Yapp (Cardiff Blues), J Thomas (Ospreys), R McCusker (Scarlets), D Peel (Sale Sharks), S Jones (Scarlets), M Stoddart (Scarlets).
Ireland: L Fitzgerald (Leinster); T Bowe (Ospreys), B O'Driscoll (Leinster, capt), G D'Arcy (Leinster), K Earls (Munster); R O'Gara (Munster), E Reddan (Leinster); C Healy (Leinster), R Best (Ulster), M Ross (Leinster), D O'Callaghan (Munster), P O'Connell (Munster), S O'Brien (Leinster), D Wallace (Munster), J Heaslip (Leinster).
Replacements: S Cronin (Connacht), T Court (Ulster), L Cullen (Leinster), D Leamy (Munster), P Stringer (Munster), J Sexton (Leinster), P Wallace (Ulster).
Angus O'Brien has quickly settled into the Wales Sevens squad after solid performances in Hong Kong and Japan. With two rounds remaining in Glasgow and Twickenham on the World Series, WRU TV's Graeme Gillespie chats to the rising star.
Wales winger Luke Morgan has established himself as one of the deadliest finishers on the Sevens World Series. WRU TV's Graeme Gillespie catches up with him on the eve of this weekend's round in Glasgow.
All roads lead to Cardiff on Sunday for the SSE SWALEC Finals Day at the Millennium Stadium. Cambrian Welfare tackle Ystradgynlais in the Bowl final, Ystrad Rhondda play Newcastle Emlyn in the Plate final while defending champions Pontypridd face Bridgend in the Cup final.
WRU Chief Executive Roger Lewis, Deputy Minister for Culture, Sport and Tourism Ken Skates and WRU Chairman Gareth Davies earlier this week launched a new competition in conjunction with the WRU unveiling its archive room.
Welsh players and management joined Deputy Minister for Sport Ken Skates at the Pierhead Building, Cardiff Bay earlier this week to reveal the Union's pioneering school-club hub initiative has been so successful the project will now almost double the scale of the original project.
The Scarlets, Newport Gwent Dragons, Cardiff Blues and the Ospreys look ahead to Judgement Day III which sees the Blues take on the Ospreys (2.30) and the Dragons tackle the Scarlets (4.45pm) at the Millennium Stadium tomorrow afternoon.
Ystradgynlais and Ynysddu played out a titanic struggle at Taffs Well in the SSE SWALEC Bowl semi-final. At the end of the game neither team could be separated after a 15-15 stalemate but Ystradgynlais go through on try count.
Blues strike first in JD III battle - Newport Gwent Dragons lock Andrew Coombs, WRU referee Dylan Llyr Jones and Cardiff Blues hooker Matthew Rees decide dressing room allocations for Judgement Day III
Wales Under 18 captain Calum Haggett has received a conditional offer to read Biomedical Science at St Anne's College, Oxford. WRU chairman Gareth Davies went to meet Calum and Coleg y Cymoedd Principal Judith Evans to wish him luck in his exams and pass on some of his personal experience.