Munster travel to Llanelli after their big European battle last weekend in Brive, knowing a win at Parc y Scarlets could secure them a league semi-final at home. Sixth placed Scarlets must win to keep their hopes of a play-off place alive.
The Scarlets will field a strong backs division for the contest with some changes to accommodate returning Scottish international Sean Lamont, with Gareth Maule playing alongisde Regan King in the centres. Wales centre Jonathan Davies is ruled out as he's still recovering from a dead leg from the Scarlets last outing against Ulster.
Wales fly-half Stephen Jones is coming back from injuring his wrist against Ulster and will start on the bench. Australian No8 David Lyons returns to the starting line-up after recovering from a knee injury.
Scarlets Head Coach Nigel Davies said: "We know Munster present us with a big physical challenge. They're a quality side and the winning mentality is engrained in them and they have the level of experience and belief to make the right decisions at key moments.
"We want to finish strongly. We've put in some big performances this season at home and on the road and our league form in the first half of the season has been a real positive. We've had an intense week in training and a lot of our internationals have been throwing themselves into the sessions and getting really stuck in despite rigors of the Six Nations and the World Cup ahead of them."
Scarlets and Wales skipper Matthew Rees said: "We have to win our next three games and on Saturday we have a tough, physical challenge ahead of us - we know how good they are in the contact area. They are the best team in the league and they're not top for nothing.
"They have strength in their squad, they are an old and experienced team that's gained a lot of success with the players they've got. No matter what team they field, they'll play with confidence and pace.
"I thought we played some great stuff out in Ulster, it was one of our best defensive performances this season and we held them. The game was there for us, it was frustrating in terms of the outcome, but we put in a performance in Ravenhill and I couldn't fault the endeavour from the players that night.
Scarlets: Morgan Stoddart, George North, Regan King, Gareth Maule, Sean Lamont, Rhys Priestland, Tavis Knoyle, Iestyn Thomas, Matthew Rees (capt), Rhys Thomas, Lou Reed, Josh Turnbull, Rob McCusker, Johnathan Edwards, David Lyons.
Replacements: Emyr Phillips, Rhodri Jones, Simon Gardiner, Aaron Shingler, Damian Welch, Gareth Davies, Stephen Jones, Scott Williams.
Munster: P Warwick; S Zebo, J Murphy, L Mafi, D Barnes; D Cusack, P Stringer; M Horan, M Sherry, S Archer; D Ryan, M O'Driscoll T O'Donnell, N Ronan, D Leamy (Capt).
Replacements: D Fogarty, D Hurley, J Hayes, A Quinlan, P Butler, D Williams, S Tuitupou, S Deasy.