Saracens stalwart, Louise Rickard, will receive her 75th cap on the left wing, with fellow veterans Claire Donovan and Kylie Wilson (captain) leading from the pack. Phil John said: "The whole squad is looking forward to getting the Six Nations campaign moving with a positive performance against England. With World Cup places still up for grabs, it is vital that we apply the pressure from the outset and perform to the pinnacle of our ability."
Wales Women: Elen Evans (Dolgellau); Manon Williams (Caernarfon), Rhian Williams (Wasps), Lowri Jones (Bala), Louise Rickard (Saracens); Awen Thomas (Cardiff Quins), Kerry Jenkins (UWIC); Amy Broadstock (Llandaff North), Jenny Davies (Caernarfon), Louise Horgan (Saracens), Claire Donovan (Saracens), Becky Dando (Cardiff Quins), Catrina Nicholas (UWIC), Kylie Wilson (Waterloo, Captain), Emma Phillips (Llandaff North)
Replacements: Nicola John (Cardiff Quins), Becky Davies (Cardiff Quins), Claire Horgan (Waterloo), Stacey Saunders (Tylorstown), Rachel Brown (Waterloo), Lucy Berry (Fishguard & Goodwick), Ayla Rose (Llandaff North)