Table-topping Narberth are unbeaten so far this season. The Otters 34-24 midweek victory over Bonymaen kept them on top of the pile.
They will be looking to consolidate their position with maximum points on Saturday when they take on Whitland.
Joint leaders Pontypool are the only other unbeaten side in the division and were unstoppable on Wednesday night hammering Tondu 50-3. Pooler entertain 4th placed Llandovery in undoubtedly the most exciting fixture of the weekend.
Llandovery are just two points off top spot following their 23-12 midweek victory over Bedwas.
Cross Keys will be hoping to get back to winning ways after they lost their unbeaten record to Tredegar on Wednesday.
It won't be plain sailing as they host Aberavon who, even at this early stage in the season, look serious title contenders.
Tredegar travel to Llanharan looking to build on their midweek victory over Cross Keys. With both sides on six points, this will be a tense and tight battle.
Tondu will be out to put their midweek hiding behind them when they travel to Cardiff hoping to teach the Glamorgan Wanderers a lesson.
However, the home side will still be reeling from their thrashing against Aberavon and will see this game as the perfect match to get back on track.
Bonymaen play Beddau, with both sides looking for a result to kick start their season.
Two sides who are yet to get up and running this year are Rumney and Treorchy.
Rumney travel to Carmarthen while bottom placed Treorchy travel to Newbridge, where Jason Williams will expect to add to his record tally of 2,283 which he achieved in midweek.
The Webb Ellis Cup visited Lampeter on Monday to recognise the fact that the town is celebrating a major milestone as it is believed the first ever game of rugby played in Wales, was in fact played in Lampeter 150 years ago.
Cardiff Blues U18 Girls will go into Sunday's Gemau Cymru with an extra spring in their step after Welsh internationals Elinor Snowsill and Philippa Tuttiett offered some last minute tips at a training session earlier this week.
Rob Howley and Josh Lewsey addressed more than 250 community club coaches and referees at the first WRU National Community Conference on the weekend. The volunteers benefitted from coaching masterclasses and workshops in a bid to connect all levels of the rugby pathway in Wales.
UEFA has today confirmed the Football Association of Wales (FAW) has been successful in its bid for the Millennium Stadium to host the 2017 UEFA Champions League Final on Saturday 3rd June, 2017 (kick-off: 19.45hrs GMT).
The winners of a filmmaking competition organised by the education charity Into Film and the WRU enjoyed a behind the scenes tour of the Millennium Stadium - and a chance to be photographed with the WRU's fire-breathing, rugby loving mascot, Scorch The Dragon, and Welsh international, Jake Ball.