Leinster's defence of their Celtic League title is in tatters after they lost their fourth match on end - 18-23 to Scottish new boys Borders.
Leinster now have to win their final two matches, secure two bonus points and hope other results go their way if they are to make the quarter-finals.
Edinburgh thumped a poor Llanelli outfit 38-14, while Ulster ended Munster's unbeaten run with a 26-17 victory at Ravenhill.
Scrum-half Neil Doak, an Ireland cricket international, scored all of Ulster's points to add some spice to the Pool A table.
Neath all but confirmed a quarter-final berth with a comfortable 34-7 win over Ebbw Vale, thanks to a hat-trick of tries to fullback Gareth Morris.
Vale flanker Tyrone Morris must have broken a record when he was sin-binned 30 seconds after coming on as a replacement, in his first appearance since being red-carded against Caerphilly a fortnight ago.
The annual Women's club launch was held at the Wales Centre of Excellence where National Women's Head Coach and Programme Lead Rhys Edwards, Competition Secretary Adrian Howell and Cardiff Met player Ffion Jones express eagerness for the new campaign to get under way.
WRU TV follows Wales' RWC training squad on day one of their camp in North Wales. The squad were greeted to an official welcome in Colwyn Bay and then headed for an afternoon of team building at ZipWorld