Leinster's defence of their Celtic League title is in tatters after they lost their fourth match on end - 18-23 to Scottish new boys Borders.
Leinster now have to win their final two matches, secure two bonus points and hope other results go their way if they are to make the quarter-finals.
Edinburgh thumped a poor Llanelli outfit 38-14, while Ulster ended Munster's unbeaten run with a 26-17 victory at Ravenhill.
Scrum-half Neil Doak, an Ireland cricket international, scored all of Ulster's points to add some spice to the Pool A table.
Neath all but confirmed a quarter-final berth with a comfortable 34-7 win over Ebbw Vale, thanks to a hat-trick of tries to fullback Gareth Morris.
Vale flanker Tyrone Morris must have broken a record when he was sin-binned 30 seconds after coming on as a replacement, in his first appearance since being red-carded against Caerphilly a fortnight ago.
The Wales Women's team headed to Dare Valley Country Park on a team bonding exercise as the entire squad got together for the very first time in preparation for this season's Six Nations championship which kicks off on Saturday with a clash against defending champions Ireland, in Donnybrook.
Wales Head Coach Warren Gatland discusses his team selection for the opening round of the RBS 6 Nations where he leads his side against Ireland, on Sunday. As WRU TV's Luke Brodley discovers, Gatland is fully aware of the challenges the defending champions pose
WRUTV caught up with Wales Women captain Rachel Taylor at the RBS 6 Nations launch and how a good crowd really helps boost the girls performance. Tickets for all three Women's home games at The Gnoll, Neath are available from www.wru.wales/tickets