Leinster's defence of their Celtic League title is in tatters after they lost their fourth match on end - 18-23 to Scottish new boys Borders.
Leinster now have to win their final two matches, secure two bonus points and hope other results go their way if they are to make the quarter-finals.
Edinburgh thumped a poor Llanelli outfit 38-14, while Ulster ended Munster's unbeaten run with a 26-17 victory at Ravenhill.
Scrum-half Neil Doak, an Ireland cricket international, scored all of Ulster's points to add some spice to the Pool A table.
Neath all but confirmed a quarter-final berth with a comfortable 34-7 win over Ebbw Vale, thanks to a hat-trick of tries to fullback Gareth Morris.
Vale flanker Tyrone Morris must have broken a record when he was sin-binned 30 seconds after coming on as a replacement, in his first appearance since being red-carded against Caerphilly a fortnight ago.
WRU TV were on hand at the launch of a major new commercial deal with WRU and Mercedes-Benz South Wales (part of the Sinclair Group), which sees the family company become an official supplier to the Welsh Rugby Union
On the back of the recent Women's Rugby World Cup, the WRU has launched a revitalised Women's and Girls domestic seasonal structure, and the future is looking bright.
Go to www.wru.co.uk/tryourgame for more information
Roger Lewis talks to WRU TV at the announcement of a new £60 million Rugby Services Agreement (RSA) which provides a new and positive contractual relationship between the WRU and its four Regions for the next six years has been agreed.
The Welsh Rugby Union has announced a major new sponsorship deal with Gullivers Sports Travel which will make the UK's leading, and longest established, multi-sport tour operator, an Official Supplier for the rest of the decade.
Having taken part in seven World Cups as a player and coach, Liza Burgess hopes to go out in style this afternoon when Wales take on Australia in the Play-off for seventh and eighth place in the Women's Rugby World Cup in Paris.