Wales captain Scott Quinnell will face the Welsh All Blacks and then miss the next two Celtic League matches, at home to Ebbw Vale and away in Edinburgh, after opting for surgery on his troublesome nose.
The big No 8 has suffered from regular nose-bleeds since he took a knock on his hooter during the British Lions tour of Australia.
He will be out for two weeks, but the Scarlets have Dave Hodges back after his duties for the United States team.
Coach Gareth Jenkins said: "It is a great blow to the side to lose someone of the calibre of Scott, but we have a strong squad to choose from and it is best to get the problem sorted sooner rather than later."
Carmarthen Quins are holding an exhibition to commemorate club players who fought in World War I. All welcome to the clubhouse on Friday afternoon to learn more about local history, or share any family anecdotes or artifacts.
Defence coach Shaun Edwards believes Saturday's clash against England - the 'form team in world rugby' - poses a huge challenge for his side but he is confident, with Wales beginning to show the defensive qualities displayed in the last two World Cups,
Women in the Ospreys region recently completed a Level 1 coaching course and are looking forward to putting their theory into practice in clubs and schools across the region. A women only course has been organised for the Scarlets region starting next week, full details at the end of the video.