Wales captain Scott Quinnell will face the Welsh All Blacks and then miss the next two Celtic League matches, at home to Ebbw Vale and away in Edinburgh, after opting for surgery on his troublesome nose.
The big No 8 has suffered from regular nose-bleeds since he took a knock on his hooter during the British Lions tour of Australia.
He will be out for two weeks, but the Scarlets have Dave Hodges back after his duties for the United States team.
Coach Gareth Jenkins said: "It is a great blow to the side to lose someone of the calibre of Scott, but we have a strong squad to choose from and it is best to get the problem sorted sooner rather than later."
The annual Women's club launch was held at the Wales Centre of Excellence where National Women's Head Coach and Programme Lead Rhys Edwards, Competition Secretary Adrian Howell and Cardiff Met player Ffion Jones express eagerness for the new campaign to get under way.
WRU TV follows Wales' RWC training squad on day one of their camp in North Wales. The squad were greeted to an official welcome in Colwyn Bay and then headed for an afternoon of team building at ZipWorld