Springbok coach Rudolf Straeuli has shuffled his side set to face Wales at Newlands on Saturday.
He has named a squad of 22 that will play in the second test after the Dragons gave them a real fright in the opening match.
In come centre De Wet Barry, openside flank Corne Krige, utility back Werner Greeff and lock Hottie Louw, while Victor Matfield, Andre Snyman, Warren Britz and, through injury, Ricardo Loubscher have been left out.
Both Krige and Barry had originally been pencilled into the squad for the first test but were struck down with a rib and ankle injury respectively.
Having recovered they have replaced Britz and Snyman who underperformed for the Boks in the 34-19 win in Bloemfontein.
Straeuli said: "It is encouraging that the likes of Krige and Barry have recovered from injury. They add depth to our 22. Naturally, there will be disappointed players, but the onus on those who have not made it is to fight their way back.
"The positive from Bloemfontein was that we won, but we as a team are constantly looking for improvement."
Meanwhile, Steve Hansen is poised to name his team for the crunch second test on Thursday with Wales' 1,000th international player Michael Owen expected to keep his place in the wake of a sensational debut.
Backs: De Wet Barry, Johannes Conradie, Craig Davidson, Werner Greeff, Adrian Jacobs, Marius Joubert, Breyton Paulse, André Pretorius, Brent Russell and Stefan Terblanché.
Forwards: James Dalton, Quinton Davids, Daan Human, Corné Krige, Jannes Labuschagne, Ollie le Roux, Hottie Louw, Willie Meyer, Faan Rautenbach, Bob Skinstad, Joe van Niekerk, AJ Venter.
Angus O'Brien has quickly settled into the Wales Sevens squad after solid performances in Hong Kong and Japan. With two rounds remaining in Glasgow and Twickenham on the World Series, WRU TV's Graeme Gillespie chats to the rising star.
Wales winger Luke Morgan has established himself as one of the deadliest finishers on the Sevens World Series. WRU TV's Graeme Gillespie catches up with him on the eve of this weekend's round in Glasgow.
All roads lead to Cardiff on Sunday for the SSE SWALEC Finals Day at the Millennium Stadium. Cambrian Welfare tackle Ystradgynlais in the Bowl final, Ystrad Rhondda play Newcastle Emlyn in the Plate final while defending champions Pontypridd face Bridgend in the Cup final.
WRU Chief Executive Roger Lewis, Deputy Minister for Culture, Sport and Tourism Ken Skates and WRU Chairman Gareth Davies earlier this week launched a new competition in conjunction with the WRU unveiling its archive room.
Welsh players and management joined Deputy Minister for Sport Ken Skates at the Pierhead Building, Cardiff Bay earlier this week to reveal the Union's pioneering school-club hub initiative has been so successful the project will now almost double the scale of the original project.
The Scarlets, Newport Gwent Dragons, Cardiff Blues and the Ospreys look ahead to Judgement Day III which sees the Blues take on the Ospreys (2.30) and the Dragons tackle the Scarlets (4.45pm) at the Millennium Stadium tomorrow afternoon.
Ystradgynlais and Ynysddu played out a titanic struggle at Taffs Well in the SSE SWALEC Bowl semi-final. At the end of the game neither team could be separated after a 15-15 stalemate but Ystradgynlais go through on try count.
Blues strike first in JD III battle - Newport Gwent Dragons lock Andrew Coombs, WRU referee Dylan Llyr Jones and Cardiff Blues hooker Matthew Rees decide dressing room allocations for Judgement Day III
Wales Under 18 captain Calum Haggett has received a conditional offer to read Biomedical Science at St Anne's College, Oxford. WRU chairman Gareth Davies went to meet Calum and Coleg y Cymoedd Principal Judith Evans to wish him luck in his exams and pass on some of his personal experience.