Springbok coach Rudolf Straeuli has shuffled his side set to face Wales at Newlands on Saturday.
He has named a squad of 22 that will play in the second test after the Dragons gave them a real fright in the opening match.
In come centre De Wet Barry, openside flank Corne Krige, utility back Werner Greeff and lock Hottie Louw, while Victor Matfield, Andre Snyman, Warren Britz and, through injury, Ricardo Loubscher have been left out.
Both Krige and Barry had originally been pencilled into the squad for the first test but were struck down with a rib and ankle injury respectively.
Having recovered they have replaced Britz and Snyman who underperformed for the Boks in the 34-19 win in Bloemfontein.
Straeuli said: "It is encouraging that the likes of Krige and Barry have recovered from injury. They add depth to our 22. Naturally, there will be disappointed players, but the onus on those who have not made it is to fight their way back.
"The positive from Bloemfontein was that we won, but we as a team are constantly looking for improvement."
Meanwhile, Steve Hansen is poised to name his team for the crunch second test on Thursday with Wales' 1,000th international player Michael Owen expected to keep his place in the wake of a sensational debut.
Backs: De Wet Barry, Johannes Conradie, Craig Davidson, Werner Greeff, Adrian Jacobs, Marius Joubert, Breyton Paulse, André Pretorius, Brent Russell and Stefan Terblanché.
Forwards: James Dalton, Quinton Davids, Daan Human, Corné Krige, Jannes Labuschagne, Ollie le Roux, Hottie Louw, Willie Meyer, Faan Rautenbach, Bob Skinstad, Joe van Niekerk, AJ Venter.
As the countdown continues for RWC2015, Tournament Chief Executive Debbie Jevans visited the Millennium Stadium to discuss preparations for the eight matches and reveal the positive news that 100,000 tickets for games at the home of Welsh rugby have sold in the last seven days.
Jason Harries is targeting a first win on the World Series circuit this season with Wales. The series returns to action this weekend in Dubai where Harries is part of a team hoping to build from its efforts in round one in October.
Wales skipper Jevon Groves says his side have addressed a few points from Gold Coast and aim to 'hit the ground running' in the next two rounds of the World Series, kicking off with this weekend in Dubai before heading off to South Africa next week.
Wales Sevens manager Steff Thomas is hopeful his side can build from a quarter-final spot in the opening round of the World Series in Australia when his side take part in the forthcoming double header in Dubai and South Africa.