Springbok coach Rudolf Straeuli has shuffled his side set to face Wales at Newlands on Saturday.
He has named a squad of 22 that will play in the second test after the Dragons gave them a real fright in the opening match.
In come centre De Wet Barry, openside flank Corne Krige, utility back Werner Greeff and lock Hottie Louw, while Victor Matfield, Andre Snyman, Warren Britz and, through injury, Ricardo Loubscher have been left out.
Both Krige and Barry had originally been pencilled into the squad for the first test but were struck down with a rib and ankle injury respectively.
Having recovered they have replaced Britz and Snyman who underperformed for the Boks in the 34-19 win in Bloemfontein.
Straeuli said: "It is encouraging that the likes of Krige and Barry have recovered from injury. They add depth to our 22. Naturally, there will be disappointed players, but the onus on those who have not made it is to fight their way back.
"The positive from Bloemfontein was that we won, but we as a team are constantly looking for improvement."
Meanwhile, Steve Hansen is poised to name his team for the crunch second test on Thursday with Wales' 1,000th international player Michael Owen expected to keep his place in the wake of a sensational debut.
Backs: De Wet Barry, Johannes Conradie, Craig Davidson, Werner Greeff, Adrian Jacobs, Marius Joubert, Breyton Paulse, André Pretorius, Brent Russell and Stefan Terblanché.
Forwards: James Dalton, Quinton Davids, Daan Human, Corné Krige, Jannes Labuschagne, Ollie le Roux, Hottie Louw, Willie Meyer, Faan Rautenbach, Bob Skinstad, Joe van Niekerk, AJ Venter.
Wales Under 20 travel to Newcastle on Friday to face England at Kingston Park. With the likes of Jack Dixon and Ashley Evans returning to the squad, it's arguably the strongest side head coach Byron Hayward has put out in the tournament so far. WRU TV previews the game with Defence Coach Richard Hodges and captain Steffan Hughes.
Wales head coach Warren Gatland gives an exclusive interview to WRU TV after naming his side to face England in the RBS 6 Nations at Twickenham on Sunday. Gatland has recalled British & Irish Lions duo Jonathan Davies and Alun Wyn Jones to his side while Rhys Webb retains his place at scrum half.
Scrum half Rhys Webb and lock Jake Ball both made their first Wales starts in last Friday's win over France at the Millennium Stadium. They talk exclusively to WRU TV's Luke Broadley about their experiences of the day.
Wales Women's Head Coach Rhys Edwards has made three changes to his side to face France at Aberavon on Sunday, where he expects his side to be given a tough time against one of the best teams in the world.