Springbok coach Rudolf Straeuli has warned Wales that his side will be pumped up for the second Test at Newlands.
He has named a side showing four changes to the team that beat Wales 34-19 at Bloemfontein on Saturday.
Stormers hard man Quinton Davids and Corne Krige have been brought in to add extra muscle to South Africa's pack.
There are also two changes behind the scrum with inside centre De Wet Barry taking over from dropped Andre Snyman.
Meanwhile, Brent Russell moves to full back with Andre Pretorius reclaiming the fly-half spot.
"I don't have to say much about Krige coming back. Loubscher was injured and we are happy with Brent playing at full-back.
"De Wet Barry is an out-and-out inside centre and it's nice to have someone like Quinton starting on his home patch."
South Africa team: Brent Russell; Stefan Terblanche, Marius Joubert, De Wet Barry, Breyton Paulse; Andre Pretorius, Johannes Conradie; Daan Human, James Dalton, Willie Meyer, Quinton Davids, Jannes Labuschagne, Corne Krige, Bobbie Skinstad (capt), Andre Venter
Replacements: Ollie le Roux, Faan Rautenbach, Hottie Louw, Joe Van Niekerk, Craig Davidson, Adrian Jacobs, Werner Greeff
WRU International Skills Coach Jason Strange is a busy man, combining the new role with that of Wales Under 20 attack coach, Ebbw Vale head coach and continuing to teach at Ebbw Fawr Learning Community.
Warren Gatland and Sam Warburton look ahead to this week's crunch RBS 6 Nations tie against France, where the Wales skipper in particular is keen to make his mark, as Paris has proved a bleak place for him in the past.
Following their historic win over England, Wales Under 20 suffered a narrow, 36-34 loss to their Scottish counterparts last weekend, despite outscoring them by five tries to three. Watch the match highlights and reaction.
WRU TV go behind the scenes with the Wales squad as they put the final touches in place ahead of the clash against Scotland at Murrayfield. Follow the squad on their captain's run, the kickers visit to Murrayfield and Neil Jenkins' press conference