Springbok coach Rudolf Straeuli has warned Wales that his side will be pumped up for the second Test at Newlands.
He has named a side showing four changes to the team that beat Wales 34-19 at Bloemfontein on Saturday.
Stormers hard man Quinton Davids and Corne Krige have been brought in to add extra muscle to South Africa's pack.
There are also two changes behind the scrum with inside centre De Wet Barry taking over from dropped Andre Snyman.
Meanwhile, Brent Russell moves to full back with Andre Pretorius reclaiming the fly-half spot.
"I don't have to say much about Krige coming back. Loubscher was injured and we are happy with Brent playing at full-back.
"De Wet Barry is an out-and-out inside centre and it's nice to have someone like Quinton starting on his home patch."
South Africa team: Brent Russell; Stefan Terblanche, Marius Joubert, De Wet Barry, Breyton Paulse; Andre Pretorius, Johannes Conradie; Daan Human, James Dalton, Willie Meyer, Quinton Davids, Jannes Labuschagne, Corne Krige, Bobbie Skinstad (capt), Andre Venter
Replacements: Ollie le Roux, Faan Rautenbach, Hottie Louw, Joe Van Niekerk, Craig Davidson, Adrian Jacobs, Werner Greeff
Wales U20 duo Leon Brown and Lloyd Lewis face a busy couple of weeks ahead. Not only will they have a Junior World Championship to take part in, they are both sitting A Level exams during the competition.
Wales U20 face a tough group in the Junior World Championship with France, England and Japan lying in wait but Attack coach Jason Strange and back rower Tom Phillips are looking forward to the campaign ahead.
Angus O'Brien has quickly settled into the Wales Sevens squad after solid performances in Hong Kong and Japan. With two rounds remaining in Glasgow and Twickenham on the World Series, WRU TV's Graeme Gillespie chats to the rising star.
Wales winger Luke Morgan has established himself as one of the deadliest finishers on the Sevens World Series. WRU TV's Graeme Gillespie catches up with him on the eve of this weekend's round in Glasgow.
All roads lead to Cardiff on Sunday for the SSE SWALEC Finals Day at the Millennium Stadium. Cambrian Welfare tackle Ystradgynlais in the Bowl final, Ystrad Rhondda play Newcastle Emlyn in the Plate final while defending champions Pontypridd face Bridgend in the Cup final.
WRU Chief Executive Roger Lewis, Deputy Minister for Culture, Sport and Tourism Ken Skates and WRU Chairman Gareth Davies earlier this week launched a new competition in conjunction with the WRU unveiling its archive room.
Welsh players and management joined Deputy Minister for Sport Ken Skates at the Pierhead Building, Cardiff Bay earlier this week to reveal the Union's pioneering school-club hub initiative has been so successful the project will now almost double the scale of the original project.
The Scarlets, Newport Gwent Dragons, Cardiff Blues and the Ospreys look ahead to Judgement Day III which sees the Blues take on the Ospreys (2.30) and the Dragons tackle the Scarlets (4.45pm) at the Millennium Stadium tomorrow afternoon.
Ystradgynlais and Ynysddu played out a titanic struggle at Taffs Well in the SSE SWALEC Bowl semi-final. At the end of the game neither team could be separated after a 15-15 stalemate but Ystradgynlais go through on try count.