Aberavon will have Danny Hawkins and Jamie Davies at half back, but Newbridge have the talented Jason Williams at fly-half, while Narberth are not in the best form, but could still pose Pontypool problems.
Bottom clubs Rumney and Treorchy have tough tasks with coach Ceri Jones taking the Zebras west to Whitland and the Cardiff-based Rumney squad going to windy Parc Mawr, where they have never beaten Bonymaen.
Bedwas hope to bounce back with a victory over Cross Keys, who have Kingsley Jones in their squad, while Tondu, fresh from winning at Beddau, have a tough task in meeting Carmarthen Quins at Pandy Park.
Glamorgan Wanderers hope to get back to winning ways at home to Llanharan and out-of -form Blackwood have a difficult task at Tredegar. In the ninth and final match, Llandovery should be too strong for Beddau and have added utility back Gareth Jones from Bonymaen to their young squad.
Click here for the results table