Wales centre Andy Marinos, Italian international full-back Matt Pini and wing Andy Wagstaff are all back in Newport's twenty-two to face Edinburgh in the opening match in Pool 5 of the Heineken Cup at Meadowbank on Frdiay night (kick-off 7.30 pm).
Newport notched their first away win in the Heineken Cup in their opening game of last season's campaign when they went to Newcastle and beat the then English Cup holders 34-21.
Edinburgh have lost only one game to date this season, at home to Munster in the Celtic League, and have a 43.75% success rate in the tournament.
"I am confident we can go here and win, and importantly I think the players are too. said Newport coach Richard Hill.
"The morale and the enthusiasm of the players over the last couple of weeks has been excellent- despite of the results." added Hill.
NEWPORT RUGBY: Shane Howarth; Andrew Wagstaff, Matt Mostyn, Andy Marinos, Luke Nabaro: Jason Strange, Ofisa Tonu'u; Rod Snow, James Richards, Chris Anthony, Simon Raiwalui (captain), Mike Voyle, Gareth Gravell, Jason Forster.Joe Powell
Matt Pini, Dale Burn, Ceri Jones, Paul Young, Andy Powell, Steve Ojomoh
As the countdown continues for RWC2015, Tournament Chief Executive Debbie Jevans visited the Millennium Stadium to discuss preparations for the eight matches and reveal the positive news that 100,000 tickets for games at the home of Welsh rugby have sold in the last seven days.
Jason Harries is targeting a first win on the World Series circuit this season with Wales. The series returns to action this weekend in Dubai where Harries is part of a team hoping to build from its efforts in round one in October.
Wales skipper Jevon Groves says his side have addressed a few points from Gold Coast and aim to 'hit the ground running' in the next two rounds of the World Series, kicking off with this weekend in Dubai before heading off to South Africa next week.
Wales Sevens manager Steff Thomas is hopeful his side can build from a quarter-final spot in the opening round of the World Series in Australia when his side take part in the forthcoming double header in Dubai and South Africa.