The International Rugby Board (IRB) has approved plans for a game between the northern and southern hemispheres in November at the Millennium Stadium in Cardiff.
The proceeds from the match, which will be played biennially in the future, will be used to assist the promotion of rugby in several financially disadvantaged countries.
Former Lions coach Syd Millar, chairman of the IRB technical committee, will appoint coaches for both teams, with Australian legend Michael Lynagh acting as match manager.
The game is planned to take place in Cardiff on 30 November at the end of the Autumn series of internationals in the northern hemisphere.
"This initiative will help re-establish and rejuvenate the game among proud rugby countries like Fiji, Samoa, Tonga and Romania," said Australian Rugby Union managing director John O'Neill.
"It will also help create a much more competitive structure at the elite level."
The IRB has also moved to stop player burn-out in the busy fixture lists of the professional era, calling on countries to make sure top players get an eight-week break during the year.
"In the interests of player welfare at the elite level, it is recommended that there should be a minimum eight-week break," the IRB said in a statement.
Leading coaches are worried that players are being forced to play too often.
After a council meeting the IRB also said it planned to take a lead in dealing with referee abuse.
It has also approved two minor law changes.
All starts and restarts of matches will be by means of a drop kick in the future instead of a place kick.
"This will come into effect on 1 June 2002 in the Southern Hemisphere in time for the Tri-Nations series and on 1 August 2002 in the Northern Hemisphere," the IRB said.
Sam Cross and Luke Treharne have been named as co-captains of the Wales Sevens side as head coach Gareth Williams names his 12-man squad to play in the first leg of the HSBC World Series in Dubai next weekend.
Bedwas head coach Steve Law and players Nicky Griffiths and Alun Rees extol the virtues of the close knit club as they prepare to host third place RGC 1404 - who are one place head of them on the Principality Premiership points table - on Saturday.
Many of the Wales squad have said Diolch (thank you) to someone who played an important part in their early playing days by nominating them to be invited to the Wales v South Africa match. One person, Gowerton Comprehensive geography teacher Mr Dean Mason was nominated by two of his former pupils, Dan Biggar and Sam Davies.
The second WRU disability rugby pilot has been delivered, this time in Caerphilly schools, culminating in a festival at the Caerphilly Centre of Sporting Excellence, Ystrad Mynach tomorrow. Plans are in place to set up a Disability Rugby Club in Newbridge to provide long-term playing opportunities.
WRU TV: Hear from inside the Wales camp as Neil Jenkins discusses this weekend's clash with South Africa and how the squad are looking to put in a strong performance to round of the 2016 Under Armour Series