Out go Naomi Thomas with a stress fracture of the shin and Hayley Baxter with a fractured scaphoid. Both UWIC players had been earmarked to play against Australia in the opening fixture and their attacking prowess will be sorely missed.
Their replacements are Cath Foale from Saracens and Gemma Allen from Tylorstown Tigers.
GB7s women left their England base to train in Wales this week. Olympic Games hopeful Rachael Burford gives WRU TV's Graeme Gillespie her thoughts on Welsh teammate Jasmine Joyce - a 'one touch wonder'
The GB7s women's squad is currently training at Wales' Centre of Excellence where assistant coach Richie Pugh tells WRU TV's Graeme Gillespie some 'tough calls' will have to be made when it comes to finalising the 12 spots for Rio's Olympic Games.
Wales U20's Billy McBryde is looking forward to starting his first game against New Zealand this afternoon in the World Rugby U20 Championship where his side are looking to gain revenge from last week's pool defeat to the Kiwis.