Out go Naomi Thomas with a stress fracture of the shin and Hayley Baxter with a fractured scaphoid. Both UWIC players had been earmarked to play against Australia in the opening fixture and their attacking prowess will be sorely missed.
Their replacements are Cath Foale from Saracens and Gemma Allen from Tylorstown Tigers.
Carmarthen Quins are holding an exhibition to commemorate club players who fought in World War I. All welcome to the clubhouse on Friday afternoon to learn more about local history, or share any family anecdotes or artifacts.
Defence coach Shaun Edwards believes Saturday's clash against England - the 'form team in world rugby' - poses a huge challenge for his side but he is confident, with Wales beginning to show the defensive qualities displayed in the last two World Cups,