Scott Quinnell is troulbled by the same knee that he hurt last summer in Australia and will miss Saturday's match against Scotland at the Millennium Stadium.
"It is the same knee, but it is a new injury," said Quinnell. "I just need a few weeks rest before the Heineken Cup semi-final for Llanelli against Leicester."
However, there was good news for Wales as Llanelli fly half Stephen Jones came through his club's Principality Cup quarter-final and also Cardiff centre Jamie Robinson was back in action in another quarter-final.
Both Robinson and his brother Nicky, along with Mark Taylor (Swansea) and Ian Gough (Newport) were in training with Wales over the weekend and Nathan Budgett (Bridgend) is hoping to be fit after limping off against LLanelli at half-time last Saturday.
Quinnell was the only one of the 22 players of the squad beaten by England at Twickenham who did not train.
The WRU has teamed up with Crawshay's to tour Georgia in June. The side, which will be called the Crawshays WRU President's XV, will play Emerging Georgia twice, in a tour which supports the Welsh Government's efforts to grow relations between the two countries.
Wales Sevens are looking to re-group after a disappointing tournament last time out in South Africa. The next double leg in New Zealand and Las Vegas offers Gareth Williams a chance to redeem themselves.
Wales Women's head coach Rhys Edwards was at Llandovery to see the conclusion of an entertaining Women's Regional championship where any one of three teams were in contention for title glory on the last day of action.