Neath have named their side to face Glasgow in the at the Gnoll on Saturday.
Coach Lyn Jones has made three changes to the side that beat the Warriors 27-20 on their turf in their last meeting.
Scrum-half Andy Moore returns to the starting line-up as does Shane Williams who takes his place on the wing.
A win is vital for the Welsh All Blacks if they are to keep their ambitions of qualifying for the Heineken Cup for the first time alive.
They currently occupy fourth place in the Welsh-Scottish League table and if they can hold on to a place in the top five, a place in Europe's premier competition will be assured.
Neath: Gareth Morris; Kevin James, James Storey, Dave Tiueti, Shane Williams; Lee Jarvis, Andy Moore; Duncan Jones, Barry Williams, Andrew Millward, Steve Martin, Gareth Llewellyn, Richard Francis, Brett Sinkinson, Nathan Bonner-Evans.
Replacements: Steve Jones, Shaun Connor, Steve Tandy, Andy Howell, Rowland Phillips, Dean Dewdney, Allan Bateman.
As the countdown continues for RWC2015, Tournament Chief Executive Debbie Jevans visited the Millennium Stadium to discuss preparations for the eight matches and reveal the positive news that 100,000 tickets for games at the home of Welsh rugby have sold in the last seven days.
Jason Harries is targeting a first win on the World Series circuit this season with Wales. The series returns to action this weekend in Dubai where Harries is part of a team hoping to build from its efforts in round one in October.
Wales skipper Jevon Groves says his side have addressed a few points from Gold Coast and aim to 'hit the ground running' in the next two rounds of the World Series, kicking off with this weekend in Dubai before heading off to South Africa next week.
Wales Sevens manager Steff Thomas is hopeful his side can build from a quarter-final spot in the opening round of the World Series in Australia when his side take part in the forthcoming double header in Dubai and South Africa.