Fly half Nicky Robinson and lock Damian Hudd, who were replacements during the match against France, replace Gavin Henson and Bryn Griffiths respectively.
Wales meet Italy for the fourth time, having won the previous matches - 78-19 at Udine in 1999; 95-0 at Newport in 2000 and 16-3 at Parma last year. Skipper Matthew Brayley and flanker Rhys Williams are the only survivors from last season's victory.
Team: 15 Gareth Swales (Swansea); 14 Liam Roberts (Cardiff), 13 Hal Luscombe (Newport), 12 Matthew Brayley (Swansea, capt), 11 Nicky Jones (UWIC); 10 Nicky Robinson (Cardiff), 9 Michael Phillips (Llanelli); 1 Paul James (Neath), 2 Adam Matthews (Neath), 3 Adam Jones (Neath), 4 Luke Tait (Cardiff), 5 Damian Hudd (Ebbw Vale), 6 Rhys Williams (Ebbw Vale), 7 Gareth Williams (Llanelli), 8 Rhys Jones (UWIC).
Replacements: 16 Matthew Miles (Northampton), 17 Phil John (Llanelli), 18 Ceiron Jones (Llanelli), 19 Bryn Griffiths (Llanelli), 20 Aled Gravelle (Llanelli), 21 Chris Miller (Cardiff), 22 Gavin Henson (Swansea)
The Welsh Rugby Union has awarded a unique 'President's Cap' to a specific group of players who represented their country between 1945 and 1979, but missed out on international recognition at the time.
Prabhat Mathema, the WRU's National Medical Manager explains the four part Pitchside Suspected Concussion Assessment process the IRB has devised that is being implemented throughout the Dove Men Series and in the LV= Cup this season, which includes the provision for a five minute temporary substitution to allow an assessment to take place.