Irish coach Eddie O'Sullivan's injury plagued build-up to his first game in charge of the national side has seen him have to rule out four senior players for the Lloyds TSB Six Nations opener against Wales at Lansdowne Road on Sunday, 3 February.
Following on from the early withdrawals of skipper Keith Wood and fellow British Lion Malcolm O'Kelly, the Ierish coach has also seen Leinster duo Shane Horgan and Eric Miller drop out. In addition, Leinster prop Emmet Byrne could also not be considered through injury.
It has meant a major reshuffle of his side and a heavy reliance on the Munster side that reached the semi-finals of the Heineken Cup for the third successive season last weekend with a magnificent victory in Paris over Stade Francais.
O'Sullivan has handed a first cap to young Munster lock Paul O'Connell, who was man of the match in Paris, in the absenece of O'Kelly, while Munster hooker Frank Sheahan comes in for Wood at hooker to make his first start in the Six Nations Championship.
That means Munster provide the whole of the front five, seven members of the pack and eight players overall to the side.
Peter Stringer appears at scrum half and to make it an even greater day for the Munster contingent, their captain Mick Galwey will lead the side in the absence of Wood and prop Peter Clohessy will win his 50th cap.
Up front, Llanelli's Simon Easterby is the odd man out, while Leicester Tigers full back Geordan Murphy comes in on the right wing. He fills in for Bath's kevin maggs, who switches to centre in the absence of Horgan.
Leinster's uncapped flanker Keith Gleeson, Dublin-born but a former captain of Australia Under 21, comes in on the replacements bench due to the absence of team mate Miller.
O'Sullivan has still to decide on a prop replacement and has named an AN Other on the bench.
Girvan Dempsey (Leinster); Geordan Murphy (Leicester Tigers), Brian O'Driscoll (Leinster), Kevin Maggs (Bath), Denis Hickie (Leinster; David Humphreys (Ulster), Peter Stringer (Munster); Peter Clohessy (Munster), Frank Sheahan (Munster), John Hayes (Munster); Mick Galwey (Munster, CAPTAIN), Paul O'Connell (Munster), Simon Easterby (Llanelli), David Wallace (Munster), Anthony Foley (Munster)
Shane Byrne (Leinster), AN Other, Gary Longwell (Ulster), Keith Gleeson (Leinster), Guy Easterby (Llanelli), Ronan O'Gara (Munster), Rob Henderson (Munster).
Whenever Bedlinog tackle Penallta a massive fixure is guaranteed but this Sunday there will be even more emphasis placed on the two rivals when they contest the SSE Swalec Plate final at Principality Stadium.
Ahead of their SSE SWALEC Bowl Final clash with Taffs Well at Principality Stadium on Sunday, Burry Port share their #FABXV nomination with WRUTV in the search for Welsh rugby's greatest volunteers. Everyone can get involved by sending nominations via twitter to @WRU_Community using the hashtag #FABXV
Cardiff Blues prop Gethin Jenkins and Ospreys centre Ben John look ahead to the first game at Principality Stadium in Saturday's double header which is promising to be a special occasion for all Welsh fans.
Carmarthen Quins Director of Rugby Ian Jones and committee member Jeff Thomas along with Llandovery chairman Handel Davies look ahead to Sunday's SSE SWALEC Cup showdown where both teams are out to prove 'West is best'
SWALEC ambassador Shane WIlliams is looking forward to Sunday's Finals Day where the Cup, Bowl and Plate offers a great opportunity for players and teams to experience the magic of playing at Principality Stadium
Carmarthen Quins coach Richard Kelly believes it is an exciting time to be part of the Scarlets region as his side take on local rivals Llandovery in the SSE Swalec Cup final on Sunday, as WRU TV's Graeme Gillespie discovers
Scarlets long serving prop Phil John talks to WRU TV's Graeme Gillespie about Judgement Day IV and SSE Swalec Cup finals day. The last time Llandovery were in the cup final in 2007, the Drovers claimed the spoils with Phil playing a major role in the engine room.
Meet Aberdare coach Luke Thomas whose #FABXV nomination goes to super volunteer Daz with a whopping 10 things he does for the club each week, all except the ironing! You can also join in the search for Welsh rugby's greatest volunteers, by sending your nomination via twitter to @WRU_Community using the hashtag #FABXV
SSE Swalec Cup kings Pontypridd travelled to Swansea, fully expecting a return to their second home but Llandovery had other ideas as they also sought victory in the semi-final to earn the right to play the final at Principality Stadium