Irish coach Eddie O'Sullivan's injury plagued build-up to his first game in charge of the national side has seen him have to rule out four senior players for the Lloyds TSB Six Nations opener against Wales at Lansdowne Road on Sunday, 3 February.
Following on from the early withdrawals of skipper Keith Wood and fellow British Lion Malcolm O'Kelly, the Ierish coach has also seen Leinster duo Shane Horgan and Eric Miller drop out. In addition, Leinster prop Emmet Byrne could also not be considered through injury.
It has meant a major reshuffle of his side and a heavy reliance on the Munster side that reached the semi-finals of the Heineken Cup for the third successive season last weekend with a magnificent victory in Paris over Stade Francais.
O'Sullivan has handed a first cap to young Munster lock Paul O'Connell, who was man of the match in Paris, in the absenece of O'Kelly, while Munster hooker Frank Sheahan comes in for Wood at hooker to make his first start in the Six Nations Championship.
That means Munster provide the whole of the front five, seven members of the pack and eight players overall to the side.
Peter Stringer appears at scrum half and to make it an even greater day for the Munster contingent, their captain Mick Galwey will lead the side in the absence of Wood and prop Peter Clohessy will win his 50th cap.
Up front, Llanelli's Simon Easterby is the odd man out, while Leicester Tigers full back Geordan Murphy comes in on the right wing. He fills in for Bath's kevin maggs, who switches to centre in the absence of Horgan.
Leinster's uncapped flanker Keith Gleeson, Dublin-born but a former captain of Australia Under 21, comes in on the replacements bench due to the absence of team mate Miller.
O'Sullivan has still to decide on a prop replacement and has named an AN Other on the bench.
Girvan Dempsey (Leinster); Geordan Murphy (Leicester Tigers), Brian O'Driscoll (Leinster), Kevin Maggs (Bath), Denis Hickie (Leinster; David Humphreys (Ulster), Peter Stringer (Munster); Peter Clohessy (Munster), Frank Sheahan (Munster), John Hayes (Munster); Mick Galwey (Munster, CAPTAIN), Paul O'Connell (Munster), Simon Easterby (Llanelli), David Wallace (Munster), Anthony Foley (Munster)
Shane Byrne (Leinster), AN Other, Gary Longwell (Ulster), Keith Gleeson (Leinster), Guy Easterby (Llanelli), Ronan O'Gara (Munster), Rob Henderson (Munster).
Wales Head Coach Rob Howley talks to WRU TV's Sebastian Barrett about the 36-man squad he has just named for the forthcoming Under Armour series, which includes two uncapped players, Ospreys duo Sam Davies and Rory Thornton.
Head coach Rowland Phillips is deligthed he can now call BT Sport Cardiff Arms Park home for his Wales Women's side, who launch their international season next month with games against Scotland and UK Armed Forces in the heart of the capital city.
Wales Sevens star Sam Cross has put his home town club of Brynmawr on the map after winning a silver medal at the Rio Olympics with Team GB. His club have now honoured him by naming their players bar after him, as WRU TV discovered at the official launch, recently.
One of the newest members of the Principality Premiership, Bargoed admit it's proving to be a steep learning curve at the highest level, but are determined to become a force to be reckoned with. WRU TV visited the club last weekend when they took on Llanelli.
Table-topping Aberavon travel to north Wales to tackle RGC 1404 as both teams defend unbeaten starts to the season in the Principality Premiership. WRU TV's Graeme Gillespie visited the Wizards to see how their preparations were going for the game of the weekend.
The Half a Game initiative is currently sweeping across Wales and proving a major success. The scheme aims to give every young player at least half a game every weekend. WRU TV recently visited a festival in Narberth where clubs have fully embraced the initiative.
Both Bargoed and Swansea were seeking their first win of the Principality Premiership season this afternoon. It proved a fruitful day for the hosts - not only did they win, but Bargoed claimed a try bonus point.
Cardiff managed to keep their unbeaten record at home intact, but only just as Bridgend made them work extremely hard before the Blue and Blacks secured a hard fought Principality Premiership win at the BT Sport Arms Park last night.
Former Wales back row Andy Powell gives a guided tour of The Wern, home of Merthyr RFC, who are determined to prove a lot of people wrong and make their mark in their first season in the Principality Premiership.