Craig Morgan, the 23-year-old Cardiff wing, will make his Wales senior debut in the opening match of the 2002 Lloyds TSB Six Nations Championship, against Ireland at Lansdowne Road, Dublin, on Sunday (2.00 pm).
Morgan is the one new cap in a side showing seven changes from the team beaten 21-13 by world champions Australia last November.
Morgan comes in on the left wing in place of Gareth Thomas with five of the changes in the pack.
British and Irish Lions tourists Dafydd James and Martyn Williams have recovered from the injuries that stopped them facing the Wallabies, James taking over from Wayne Proctor on the right wing and Williams packing down at openside flanker in place of Brett Sinkinson.
It is all change in the second row, Craig Quinnell and Chris Wyatt taking over from Ian Gough and Andy Moore, with Chris Anthony replacing Darren Morris at tighthead prop and Nathan Budgett packing down at blindside flanker in place of Colin Charvis.
Rob Howley will become Wales' most capped scrum half, making his 55th appearance, one more than Robert Jones, with Scott Quinnell captaining Wales in the Championship for the first time.
"I have admired Craig Morgan's talents for some time and now that he has had a run of games he is ready to step up a level," said National Coach Graham Henry.
"To open the Championship in Dublin is a tough call. The Irish game has moved on and is now as refined as any in the Six Nations.
"However, our selection proves we are travelling in a positive mood. We feel the team has the ingredients - footballing skills, pace and ball winning capacity - to compete with anyone.
"We have had some extra time together in preparation and that should certainly help mould those elements into a team."
New cap Morgan said: "I am obviously delighted to have been selected, having overcome a frustrating period with injury.
"My confidence is back and all I can hope for is to be able to contribute fully to a team success in Dublin."
15 Kevin Morgan (Swansea)
14 Dafydd James (Bridgend)
13 Jamie Robinson (Cardiff)
12 Iestyn Harris (Cardiff)
11 Craig Morgan (Cardiff)
10 Stephen Jones (Llanelli)
9 Robert Howley (Cardiff)
1 Spencer John (Cardiff)
2 Robin McBryde (Llanelli)
3 Chris Anthony (Newport Rugby)
4 Craig Quinnell (Cardiff)
5 Chris Wyatt (Llanelli)
6 Nathan Budgett (Bridgend)
7 Martyn Williams (Cardiff)
8 Scott Quinnell (Llanelli, captain)
16 Barry Williams (Neath)
17 Duncan Jones (Neath)
18 Ian Gough (Newport Rugby)
19 Brett Sinkinson (Neath)
20 Dwayne Peel (Llanelli)
21 Andy Marinos (Newport Rugby)
22 Rhys Williams (Cardiff)
Beating Merthyr has boosted Carmarthen Quins hopes of reaching a top eight spot in the Principality Premiership. Quins captain Haydn Pugh is delighted with his team's progress and is determined that everyone from the Under 6s through to the senior team, enjoys the ride.
When the Wales squad were asked to nominate individuals who played a big part in their early playing days, Wales and Dragons full back and wing Hallam Amos thought of his former Monmouth School rugby coach John Bevan.
Sam Cross and Luke Treharne have been named as co-captains of the Wales Sevens side as head coach Gareth Williams names his 12-man squad to play in the first leg of the HSBC World Series in Dubai next weekend.
Bedwas head coach Steve Law and players Nicky Griffiths and Alun Rees extol the virtues of the close knit club as they prepare to host third place RGC 1404 - who are one place head of them on the Principality Premiership points table - on Saturday.
Many of the Wales squad have said Diolch (thank you) to someone who played an important part in their early playing days by nominating them to be invited to the Wales v South Africa match. One person, Gowerton Comprehensive geography teacher Mr Dean Mason was nominated by two of his former pupils, Dan Biggar and Sam Davies.
The second WRU disability rugby pilot has been delivered, this time in Caerphilly schools, culminating in a festival at the Caerphilly Centre of Sporting Excellence, Ystrad Mynach tomorrow. Plans are in place to set up a Disability Rugby Club in Newbridge to provide long-term playing opportunities.
WRU TV: Hear from inside the Wales camp as Neil Jenkins discusses this weekend's clash with South Africa and how the squad are looking to put in a strong performance to round of the 2016 Under Armour Series