Principality Cup holders Newport will launch their defence of the title at First Division Bonymaen.
Bonymaen are one of six First Diviasion clubs to reach the last 16 and their reward, along with Aberavon, Blackwood, Carmarthen Quins, Newbridge, Pontypool, as welklk as Second Divison leaders Narberth, are home ties in the seventh round.
That means a potentially lucrative clash with a Welsh/Scottish League club, who this season agreed to be drawn away from home at this stage.
Ebbw Vale's victory at Llandovery in round six earned them a home draw and they will face fellow Premiership side Neath.
First Division leaders Aberavon will host Cardiff in a game that sees the two sides clash for a sixth time in the cup. Cardiff currently lead 3-2.
Newbridge will meet Llanelli, a team they once faced in the semi-finals, while Pontypool's showdown with Swansea is a repeat of their 1983 Cup final meeting when the Gwwent side won the title for the first time.
Warren Gatland and Sam Warburton look ahead to this week's crunch RBS 6 Nations tie against France, where the Wales skipper in particular is keen to make his mark, as Paris has proved a bleak place for him in the past.
Following their historic win over England, Wales Under 20 suffered a narrow, 36-34 loss to their Scottish counterparts last weekend, despite outscoring them by five tries to three. Watch the match highlights and reaction.
WRU TV go behind the scenes with the Wales squad as they put the final touches in place ahead of the clash against Scotland at Murrayfield. Follow the squad on their captain's run, the kickers visit to Murrayfield and Neil Jenkins' press conference