Wales under-19's make seven changes from the lineup that began against the New Zealand Schools earlier this month when they take on their England counterparts at Twickenham on Wednesday (4.00pm).
After two good performances that both ended in narrow defeats - 23-22 to Australian Schools and 17-9 to New Zealand - Wales will look to repeat last February's 13-6 win at Llanelli over England.
Three of last season's winning squad are included with hooker Huw Bennett and lock Luke Charteris again in the starting lineup and Adam Yelland again as reserve hooker.
James Malpas and skipper Ioan Cunningham were in the Junior World Cup squad last season, along with Charteris and Bennett.
Here is the Squad in full. T Williams (Wellington Coll); D Tame (Cardiff), R Payne (Rhymney CS), L Thomas (New Coll), M Nuthall (Ynysybwl); M Jones (Neath Coll), R Wells (Christ Coll); I George (Newport), H Bennett (Swansea), N Williams (Llandovery), J Mills (Colston's), L Charteris (Newport), I Cunningham (Llanelli, capt), J Malpas (Cardiff), J Edwards (Rhydyfelen).
Replacements: N MacLeod (Cardiff), R Morgan (Aberavon), D Maddocks (Llanelli), I Ohlssen (Swansea), A Yelland (LLanelli), M Jones (Caernarfon), G Williams (Merthyr).
Beating Merthyr has boosted Carmarthen Quins hopes of reaching a top eight spot in the Principality Premiership. Quins captain Haydn Pugh is delighted with his team's progress and is determined that everyone from the Under 6s through to the senior team, enjoys the ride.
When the Wales squad were asked to nominate individuals who played a big part in their early playing days, Wales and Dragons full back and wing Hallam Amos thought of his former Monmouth School rugby coach John Bevan.
Sam Cross and Luke Treharne have been named as co-captains of the Wales Sevens side as head coach Gareth Williams names his 12-man squad to play in the first leg of the HSBC World Series in Dubai next weekend.
Bedwas head coach Steve Law and players Nicky Griffiths and Alun Rees extol the virtues of the close knit club as they prepare to host third place RGC 1404 - who are one place head of them on the Principality Premiership points table - on Saturday.
Many of the Wales squad have said Diolch (thank you) to someone who played an important part in their early playing days by nominating them to be invited to the Wales v South Africa match. One person, Gowerton Comprehensive geography teacher Mr Dean Mason was nominated by two of his former pupils, Dan Biggar and Sam Davies.
The second WRU disability rugby pilot has been delivered, this time in Caerphilly schools, culminating in a festival at the Caerphilly Centre of Sporting Excellence, Ystrad Mynach tomorrow. Plans are in place to set up a Disability Rugby Club in Newbridge to provide long-term playing opportunities.
WRU TV: Hear from inside the Wales camp as Neil Jenkins discusses this weekend's clash with South Africa and how the squad are looking to put in a strong performance to round of the 2016 Under Armour Series