Cardiff can do Newport a good turn by defeating Llanelli at the Arms Park on Friday and leaving Newport with a title chance if they in turn beat Bridgend on Saturday.
If Cardiff win and Newport lose, it would be Cardiff's title, but if Llanelli win on Friday, they will be the champions.
The three clubs, plus current leaders Neath, have already secured places in next season's Heineken Cup, with the fifth place going to Swansea or Pontypridd - the latter gaining the place if they defeat Sale Sharks and win the Parker Pen Shield on May 26 at Oxford.
The current Welsh/Scottish League table for the top seven clubs is: -
The last five years have been an emotional rollercoaster on and off the pitch for RGC1404. Promotion to the Principality Premiership was the culmination of five years of hard work and investment in North Wales. WRU TV caught up with prop Joe Simpson, who was one of the first intake of WRU North Wales Academy players in 2010.
Ebbw Vale captain Damien Hudd picked up the biggest accolade of the night at the 11th Principality Premiership Awards Evening held at Principality Stadium, after leading his side to the title for the first time.
Wales assistant coach Robin McBryde is predicting a tough battle against England on Sunday despite the fact they may not be considered to be at full strength. Players will be out to impress Eddie Jones which makes England a dangerous proposition, he says.
Wales U20 captain Tom Phillips and performance psychologist Dr Rich Neil explain why spending three days at Monmouth RFC has further strengthened the togetherness of the squad ahead of the #WorldRugbyU20s