There have been several changes to the starting line up following their defeat to Australia on Monday.
Youngster Kerry Jenkins replaces scrum half Cath Walkley and Awen Thomas replaces Rhian Wilmott at fly half, who has struggled with injuries this season.
Catrin Edwards continues to impress in the front row and is joined by the familiar faces of Dawn Mason and Jamie Kift.
Claire Donovan has been dropped and April Dent moves from her usual position at No 8 to take her place in the second row. Kylie Wilson wears the No. 8 shirt with all-rounder Jackie Morgan at Flanker.
The backs remain the same with Flowers and Jones on the wings with captain Melissa Berry and Louise Rickard in the centre. Caernarfon's Kate Jones plays at full back.
Wales have to win by 21 points to secure the second place position in their pool. Germany lost their first round game to the favourites, New Zealand 117-0, so the Welsh squad are confident of victory this afternoon. The game kicks off at 4.30pm (local time)
1 Dawn Mason
2 Jamie Kift
3 Catrin Edwards
4 April Dent
5 Liza Burgess
6 Jackie Morgan
7 Pip Minto
8 Kylie Wilson
9 Kerry Jenkins
10 Awen Thomas
11 Sue Jones
12 Melissa Berry
13 Louise Rickard
14 Claire Flowers
15 Kate Jones
Dodgy tattoos, carthorses, Avatar and soft chins are revealed by Wales Sevens players Tom Williams and Sam Cross as they profile the Wales Sevens squad taking part in Hong Kong this weekend in the latest round of the HSBC Sevens World Series.
The youngest member of the Wales Women's squad, Keira Bevan, is hoping to repay the faith shown in her when she starts her first Six Nations game against Italy tomorrow evening in the final round of the championship.
Sevens head coach Gareth Williams is a happy man after drafting in full internationals Rhodri Williams and Adam Warren for the next two rounds of the world series in Hong Kong and Japan, as WRU TV's Graeme Gillespie discovers.