However the Gnoll side still have to hope that the Arms Park youngsters lose both their remaining games to enable them to snatch the title. Neath have to play Llanelli away while Cardiff are at home to Pontypridd and away to Bridgend.
Wing Richard Carter again impressed crossing for a brace of tries and fly half Dylan Pugh maintained his recent league form by scoring a try as well as landing a penalty and a conversion. The forwards secured a penalty try while flanker Steve Tandy sealed Neaths eleventh victory in the league with a second half try.
Michael Hook replied with a brace of penalties and conversions as well as landing a drop goal while full back James Rowles and centre Scott Williams crossed for tries.
The Gnoll U'21s had secured a weekend victory after they defeated a Combined Services side by 19pts to 10 last sunday.
Lloyd Hayden crossed for a brace of tries while Shaun Connor added both conversions as Neath lead by 14pts to nil at the interval. A further try from lock Craig Jones secured an impressive win for the home side.
As the countdown continues for RWC2015, Tournament Chief Executive Debbie Jevans visited the Millennium Stadium to discuss preparations for the eight matches and reveal the positive news that 100,000 tickets for games at the home of Welsh rugby have sold in the last seven days.
Jason Harries is targeting a first win on the World Series circuit this season with Wales. The series returns to action this weekend in Dubai where Harries is part of a team hoping to build from its efforts in round one in October.
Wales skipper Jevon Groves says his side have addressed a few points from Gold Coast and aim to 'hit the ground running' in the next two rounds of the World Series, kicking off with this weekend in Dubai before heading off to South Africa next week.
Wales Sevens manager Steff Thomas is hopeful his side can build from a quarter-final spot in the opening round of the World Series in Australia when his side take part in the forthcoming double header in Dubai and South Africa.