Wales Under 21 have lost Cardiff outside half Nicky Robinson to the senior Wales replacements bench at Twickenham following the injury to Stephen Jones.
And with the IRB Young Player of the Year, Swansea's Gavin Henson, ruled out with an injury, it means Newport's Michael Hook will win his first Under 21 cap in the No 10 jersey against England Under 21 at Newbury tonight (kick-off 7.30pm).
Wales will be seeking their fourth successive victory over England in the Six Nations Under 21 Championship. They also beat them in Argentina in an eight-team tournament in 2000.
England's only victory against Wales was in their first meeting in 1998 at
Worcester, winning 46-7.
In their Championship clashes, Wales won 36-21 at Neath in 1999, 15-12 at New Brighton in 2000 and 27-12 at Pontypridd last year.
After winning in Ireland and losing at home to France, Wales defeated Italy at Bridgend by 65-12. They have made a number of changes from that game, including bringing in Wales A No 8 Andrew Powell.
ENGLAND UNDER 21 (v Wales Under 21)
Jon Goodridge (Gloucester); Anthony Elliott (Sale Sharks), Adam Billig (Leicester Tigers), Alex Crockett (Bath), Tom Voyce (Bath); Oliver Barkley (Bath), Ian Vass (Northampton Saints); Michael Holford (Leicester Tigers), Jonathan Roddam (NEC Harlequins), Mark Irish (Gloucester),
Stuart Hooper (Saracens), Martin Purdy (London Wasps), Chris Morgan (Bristol Shoguns), James Scaysbrook (Bath), Mark Soden (Northampton Saints, Captain)
Replacements: Alex Page (London Wasps),
Andy Higgins (Bristol Shoguns), Nick Cox (Gloucester), James Buckland (Northampton Saints), Alistair McKenzie (London Wasps), James Hamilton (Leicester Tigers), Ian Clarke (Leeds Tykes)
WALES UNDER 21
Gareth Swales (Swansea); James Strong (London Welsh), Hal Luscombe (Newport), Matthew Brayley (Swansea, capt), Liam Roberts (Cardiff); Michael Hook (Newport), Michael Phillips (Llanelli);
Paul James (Neath), Adam Matthews (Neath), Adam Jones (Neath), Luke
Tait (Cardiff), Ryan Jones (UWIC), Rhys Williams (Ebbw Vale), Gareth Williams (Llanelli), Andrew Powell (Newport).
Replacements: Matthew Miles (Northampton Saints), Phil John (Llanelli), Ceiron Jones (Llanelli), Nathan Brew (Newport), Rhys Jones
(Newport), Chris Miller (Cardiff), Dafydd Lewis (London Wasps).
Wales Head Coach Rob Howley talks to WRU TV's Sebastian Barrett about the 36-man squad he has just named for the forthcoming Under Armour series, which includes two uncapped players, Ospreys duo Sam Davies and Rory Thornton.
Head coach Rowland Phillips is deligthed he can now call BT Sport Cardiff Arms Park home for his Wales Women's side, who launch their international season next month with games against Scotland and UK Armed Forces in the heart of the capital city.
Wales Sevens star Sam Cross has put his home town club of Brynmawr on the map after winning a silver medal at the Rio Olympics with Team GB. His club have now honoured him by naming their players bar after him, as WRU TV discovered at the official launch, recently.
One of the newest members of the Principality Premiership, Bargoed admit it's proving to be a steep learning curve at the highest level, but are determined to become a force to be reckoned with. WRU TV visited the club last weekend when they took on Llanelli.
Table-topping Aberavon travel to north Wales to tackle RGC 1404 as both teams defend unbeaten starts to the season in the Principality Premiership. WRU TV's Graeme Gillespie visited the Wizards to see how their preparations were going for the game of the weekend.
The Half a Game initiative is currently sweeping across Wales and proving a major success. The scheme aims to give every young player at least half a game every weekend. WRU TV recently visited a festival in Narberth where clubs have fully embraced the initiative.
Both Bargoed and Swansea were seeking their first win of the Principality Premiership season this afternoon. It proved a fruitful day for the hosts - not only did they win, but Bargoed claimed a try bonus point.
Cardiff managed to keep their unbeaten record at home intact, but only just as Bridgend made them work extremely hard before the Blue and Blacks secured a hard fought Principality Premiership win at the BT Sport Arms Park last night.
Former Wales back row Andy Powell gives a guided tour of The Wern, home of Merthyr RFC, who are determined to prove a lot of people wrong and make their mark in their first season in the Principality Premiership.