It will be the biggest upset since David slew Goliath - or so say the bookies!
England are quoted at 1/33 to complete the Triple Crown against Wales at Twickenham on Saturday, with Scott Quinnell's side an incredible 10/1 against doing another 'Wembley'.
But what do the bookies know? It's what the real fans think that is important.
And on that score, 58% of the 4,000 people who answered our poll felt it is possible for the 'Mighty Quinn' and his red army to write another page in the rich history of Welsh rugby.
In fact, 2,329 of you voted for a Welsh success at the weekend, while 1,681 felt victory is beyond Scott and co.
I think Steve Hansen and his coaching team might take issue with the view of the latter group!
The Wales Women's team headed to Dare Valley Country Park on a team bonding exercise as the entire squad got together for the very first time in preparation for this season's Six Nations championship which kicks off on Saturday with a clash against defending champions Ireland, in Donnybrook.
Wales Head Coach Warren Gatland discusses his team selection for the opening round of the RBS 6 Nations where he leads his side against Ireland, on Sunday. As WRU TV's Luke Brodley discovers, Gatland is fully aware of the challenges the defending champions pose
WRUTV caught up with Wales Women captain Rachel Taylor at the RBS 6 Nations launch and how a good crowd really helps boost the girls performance. Tickets for all three Women's home games at The Gnoll, Neath are available from www.wru.wales/tickets