It will be the biggest upset since David slew Goliath - or so say the bookies!
England are quoted at 1/33 to complete the Triple Crown against Wales at Twickenham on Saturday, with Scott Quinnell's side an incredible 10/1 against doing another 'Wembley'.
But what do the bookies know? It's what the real fans think that is important.
And on that score, 58% of the 4,000 people who answered our poll felt it is possible for the 'Mighty Quinn' and his red army to write another page in the rich history of Welsh rugby.
In fact, 2,329 of you voted for a Welsh success at the weekend, while 1,681 felt victory is beyond Scott and co.
I think Steve Hansen and his coaching team might take issue with the view of the latter group!
The last five years have been an emotional rollercoaster on and off the pitch for RGC1404. Promotion to the Principality Premiership was the culmination of five years of hard work and investment in North Wales. WRU TV caught up with prop Joe Simpson, who was one of the first intake of WRU North Wales Academy players in 2010.
Ebbw Vale captain Damien Hudd picked up the biggest accolade of the night at the 11th Principality Premiership Awards Evening held at Principality Stadium, after leading his side to the title for the first time.
Wales assistant coach Robin McBryde is predicting a tough battle against England on Sunday despite the fact they may not be considered to be at full strength. Players will be out to impress Eddie Jones which makes England a dangerous proposition, he says.
Wales U20 captain Tom Phillips and performance psychologist Dr Rich Neil explain why spending three days at Monmouth RFC has further strengthened the togetherness of the squad ahead of the #WorldRugbyU20s