Cardiff Blues and former Wales Under 21 prop Gary Powell has been forced to retire due to injury.
The 31-year-old tore his achilles in the Magners League match against Leinster in March and the injury has not healed well enough for him to resume playing at the highest level.
Powell becomes the second Blues player forced into retirement this season, after Gareth Cooper's announcement earlier this year.
He played for Wales Schools before joining Cardiff RFC in 1999 and went onto play 44 first-team games before moving to Richmond.
During his career, the tight head prop also played for Leeds Tykes and Gloucester before returning to Cardiff Blues in 2006 and playing a further 80 matches for the top side in the Welsh capital.
Powell now joins former Wales and British & Irish Lions scrum half Gareth Cooper in hanging up his boots this season. Cooper left the club after failing to overcome a nagging groin problem that had forced him to undergo three separate operations earlier in his career.
"I've worked extremely hard to overcome this injury but, in the end, I've been advised by my consultant that my achilles will not stand up to the demands of the game. It is hugely disappointing," said Powell
"I have played with some great players and made many lifelong friends throughout my career. There have been huge changes at Cardiff Blues since I first joined in 1999 and I wish them every success in the future."
"Playing rugby has been a large part of my life for many years since I first started at Treherbert RFC. However, I have a young family and it is now time to look to the future and enjoy the next chapter of my life."
Sam Cross and Luke Treharne have been named as co-captains of the Wales Sevens side as head coach Gareth Williams names his 12-man squad to play in the first leg of the HSBC World Series in Dubai next weekend.
Bedwas head coach Steve Law and players Nicky Griffiths and Alun Rees extol the virtues of the close knit club as they prepare to host third place RGC 1404 - who are one place head of them on the Principality Premiership points table - on Saturday.
Many of the Wales squad have said Diolch (thank you) to someone who played an important part in their early playing days by nominating them to be invited to the Wales v South Africa match. One person, Gowerton Comprehensive geography teacher Mr Dean Mason was nominated by two of his former pupils, Dan Biggar and Sam Davies.
The second WRU disability rugby pilot has been delivered, this time in Caerphilly schools, culminating in a festival at the Caerphilly Centre of Sporting Excellence, Ystrad Mynach tomorrow. Plans are in place to set up a Disability Rugby Club in Newbridge to provide long-term playing opportunities.
WRU TV: Hear from inside the Wales camp as Neil Jenkins discusses this weekend's clash with South Africa and how the squad are looking to put in a strong performance to round of the 2016 Under Armour Series